SCHEMBL870765

SCHEMBL870765

O=S(=O)(O)c1nc2c(ccc3c(-c4ccccc4)ccnc32)c(-c2ccccc2)c1S(=O)(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP2A P11388 3/20 0.40
CKS1B P61024 7/20 0.38
SKP2 Q13309 7/20 0.38
GLO1 Q04760 2/20 0.38
MMP2 P08253 2/20 0.36
ALDH1A1 P00352 1/20 0.35
NR1H2 P55055 4/20 0.34
NR1H3 Q13133 4/20 0.34
IKBKB O14920 1/20 0.33
CHUK O15111 1/20 0.33
DAPK3 O43293 1/20 0.33
JAK2 O60674 1/20 0.33
PRKD3 O94806 1/20 0.33
MAP4K4 O95819 1/20 0.33
PAK4 O96013 1/20 0.33
CSF1R P07333 1/20 0.33
RET P07949 1/20 0.33
IGF1R P08069 1/20 0.33
FGFR1 P11362 1/20 0.33
PRKACA P17612 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL597833 1.00 TOP2A (0.40) TOP2ACKS1BSKP2GLO1MMP2
SCHEMBL7873518 0.99 TOP2A (0.39) TOP2ACKS1BSKP2GLO1MMP2
SCHEMBL6037850 0.99 TOP2A (0.39) TOP2ACKS1BSKP2GLO1MMP2
SCHEMBL27805381 0.99 TOP2A (0.39) TOP2ACKS1BSKP2GLO1MMP2
Water SCHEMBL8819292 0.98 TOP2A (0.38) TOP2ACKS1BSKP2GLO1MMP2
SCHEMBL29026621 0.98 TOP2A (0.38) TOP2ACKS1BSKP2GLO1MMP2
SCHEMBL15570898 0.94 TOP2A (0.36) TOP2ACKS1BSKP2GLO1MMP2
SCHEMBL4892330 0.92 TOP2A (0.38) TOP2ACKS1BSKP2GLO1MMP2
SCHEMBL9770996 0.83 CKS1B (0.38) TOP2ACKS1BSKP2GLO1MMP2
SCHEMBL8140844 0.83 CKS1B (0.38) TOP2ACKS1BSKP2GLO1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 605 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260016484-A1 SUPEROXIDE-RESPONSIVE QUINONE METHIDE PRECURSOR (QMP-SO) AND METHOD OF USE UNIV HONG KONG (HK) 2026-01-15 US claimed
US-20240132875-A1 Single-Molecule Phenotype Analysis The Trustees of the California State University (US) 2024-04-25 US claimed
EP-4304317-A1 PEROVSKITE SOLAR CELL AND PREPARATION METHOD THEREFOR China Three Gorges Co., Ltd. (CN) 2024-01-10 EP claimed
US-20230313033-A1 Nanoparticles To Improve Analytical Signal Alma Mater Studiorum - Università di Bologna (IT) 2023-10-05 US claimed
EP-4211079-A1 NANOPARTICLES TO IMPROVE ANALYTICAL SIGNAL Alma Mater Studiorum Universita di Bologna (IT) 2023-07-19 EP claimed
WO-2022053965-A1 NANOPARTICLES TO IMPROVE ANALYTICAL SIGNAL ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNA (IT) 2022-03-17 WO claimed
CN-108148507-B Polishing composition for fused quartz 清华大学 2020-12-04 CN claimed
EP-1599555-B1 CMP COMPOSITION COMPRISING A SULFONIC ACID AND A METHOD FOR POLISHING NOBLE METALS CABOT MICROELECTRONICS CORP (US) 2019-06-12 EP claimed
CN-105543335-B Method for determining activity of acid phosphatase 南京理工大学 2019-05-31 CN claimed
EP-2535423-B1 Labeling and detection of nucleic acids LIFE TECHNOLOGIES CORP (US) 2019-05-15 EP claimed
WO-1997020213-A1 LUMINESCENT PROBES FOR PROTEIN DETECTION TRUSTEES OF BOSTON UNIVERSITY (US) 1997-06-05 WO claimed
WO-1996034977-A1 DETERMINATION OF GLYCATED PROTEINS GENZYME LIMITED (GB) 1996-11-07 WO claimed
EP-0525070-B1 PHOTOVOLTAIC CELLS ECOLE POLYTECH (CH) 1995-12-20 EP claimed
EP-0527186-A4 UNIV ILLINOIS (US) 1995-01-18 EP claimed
EP-0527186-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS The Board of Trustees for the University of Illinois (US) 1993-02-17 EP claimed
EP-0525070-A1 PHOTOVOLTAIC CELLS. GRAETZEL MICHAEL (CH) 1993-02-03 EP claimed
WO-1991016820-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1991-11-14 WO claimed
WO-1991016719-A2 PHOTOVOLTAIC CELLS GRAETZEL MICHAEL (CH) 1991-10-31 WO claimed
US-4777261-A Preparation of 2-benzoxazolones SHELL OIL COMPANY (US) 1988-10-11 US claimed
US-4238197-A SOLVENT EXTRACTION, REDUCTION, CHELATING, COLORIMETRIC ANALYSIS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1980-12-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260016484-A1 SUPEROXIDE-RESPONSIVE QUINONE METHIDE PRECURSOR (QMP-SO) AND METHOD OF USE SQOR, TXN2, CHAMP1 TOP2A 1920/4885CKS1B 711/4885SKP2 398/4885
US-20240132875-A1 Single-Molecule Phenotype Analysis FBL, SRPRB, PABPC4 TOP2A 2526/4885CKS1B 2827/4885SKP2 3517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.