SCHEMBL787366

SCHEMBL787366

CC1(C)c2ccccc2-c2ccc(-c3cccc4c3oc3c(-c5ccc6[nH]c7ccccc7c6c5)cccc34)cc21

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.36
AHR P35869 1/20 0.36
KIF11 P52732 4/20 0.35
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 2/20 0.35
HSD17B10 Q99714 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPT P10636 2/20 0.35
MEN1 O00255 1/20 0.35
HPGD P15428 1/20 0.35
PGR P06401 4/20 0.34
GPR3 P46089 1/20 0.33
MTNR1A P48039 1/20 0.32
MTNR1B P49286 1/20 0.32
PRKDC P78527 1/20 0.31
PDK2 Q15119 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10226914 0.98 ALOX5 (0.38) ALOX5AHRKIF11KDM4EALDH1A1
SCHEMBL788770 0.90 ALOX5 (0.47) ALOX5KMT2AMEN1PGRPRKDC
SCHEMBL19061441 0.89 AHR (0.42) AHRKIF11KDM4EALDH1A1HSD17B10
SCHEMBL16442721 0.88 AHR (0.43) AHRKIF11KDM4EALDH1A1HSD17B10
SCHEMBL19041626 0.87 AHR (0.40) AHRKIF11KDM4EALDH1A1HSD17B10
SCHEMBL19061342 0.86 AHR (0.42) AHRKIF11KDM4EALDH1A1HSD17B10
SCHEMBL1637339 0.85 ALOX5 (0.43) ALOX5PRKDCPDK2
SCHEMBL788711 0.85 ALOX5 (0.33) ALOX5AHRKIF11KDM4EALDH1A1
SCHEMBL782103 0.84 ALOX5 (0.46) ALOX5AHRKMT2AMEN1PGR
SCHEMBL10227385 0.84 ALOX5 (0.39) ALOX5AHRKIF11KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 ALOX5 1162/4885AHR 71/4885KIF11 1085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.