SCHEMBL788770

SCHEMBL788770

CC1(C)c2ccccc2-c2ccc(-c3ccc4[nH]c5ccc(-c6cccc7c6oc6ccccc67)cc5c4c3)cc21

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.47
PRKDC P78527 4/20 0.39
GGPS1 O95749 1/20 0.37
PTGES2 Q9H7Z7 1/20 0.35
CASP3 P42574 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
PGR P06401 2/20 0.32
MEN1 O00255 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
HCRTR1 O43613 1/20 0.32
AVPR1A P37288 1/20 0.31
PRMT5 O14744 1/20 0.31
WDR77 Q9BQA1 1/20 0.31
ATM Q13315 1/20 0.31
PDK2 Q15119 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL782103 0.93 ALOX5 (0.46) ALOX5PRKDCGGPS1PTGES2CASP3
SCHEMBL10226914 0.92 ALOX5 (0.38) ALOX5PRKDCPGRMEN1KMT2A
SCHEMBL16017825 0.91 ALOX5 (0.56) ALOX5PRKDCGGPS1PTGES2PGR
SCHEMBL787366 0.90 ALOX5 (0.36) ALOX5PRKDCPGRMEN1KMT2A
SCHEMBL12324541 0.90 ALOX5 (0.57) ALOX5PRKDCGGPS1PTGES2PGR
SCHEMBL18086150 0.89 ALOX5 (0.53) ALOX5PRKDCGGPS1PTGES2MEN1
SCHEMBL20276869 0.87 ALOX5 (0.59) ALOX5PRKDCGGPS1PTGES2PGR
SCHEMBL788568 0.87 ALOX5 (0.32) ALOX5CASP3SENP7SENP6
SCHEMBL18826110 0.87 ALOX5 (0.49) ALOX5PRKDCGGPS1PTGES2PGR
SCHEMBL788711 0.86 ALOX5 (0.33) ALOX5CASP3SENP7SENP6PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 ALOX5 1162/4885PRKDC 3567/4885GGPS1 2063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.