Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7873784 | 0.89 | ALDH1A1 (0.55) | CYP19A1ALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL7879552 | 0.89 | CYP19A1 (0.64) | CYP19A1ALDH1A1POLB | |
| SCHEMBL7876913 | 0.87 | ALDH1A1 (0.53) | CYP19A1ALDH1A1SMN1; SMN2POLBTSHR | |
| SCHEMBL7868654 | 0.86 | ALDH1A1 (0.52) | CYP19A1ALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL7879591 | 0.86 | ALDH1A1 (0.52) | CYP19A1ALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL7873708 | 0.85 | CYP19A1 (0.51) | CYP19A1ALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL10838763 | 0.83 | ALDH1A1 (0.76) | CYP19A1ALDH1A1POLBMAPTTSHR | |
| SCHEMBL10838517 | 0.80 | ALDH1A1 (0.70) | CYP19A1ALDH1A1POLBMAPTTSHR | |
| SCHEMBL9268617 | 0.79 | ALDH1A1 (0.42) | CYP19A1ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL7877387 | 0.78 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2POLBLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326500-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | ABBOTT LABORATORIES | 2001-12-04 | — | — | US | disclosed |
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |