Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868654 | 0.91 | ALDH1A1 (0.52) | ALDH1A1KMT2ASMN1; SMN2CYP19A1LMNA | |
| SCHEMBL9268617 | 0.89 | ALDH1A1 (0.42) | ALDH1A1KMT2ASMN1; SMN2CYP19A1LMNA | |
| SCHEMBL7873784 | 0.87 | ALDH1A1 (0.55) | ALDH1A1KMT2ASMN1; SMN2CYP19A1LMNA | |
| SCHEMBL7873778 | 0.86 | CYP19A1 (0.54) | ALDH1A1SMN1; SMN2CYP19A1LMNAHTT | |
| SCHEMBL7876913 | 0.85 | ALDH1A1 (0.53) | ALDH1A1KMT2ASMN1; SMN2CYP19A1LMNA | |
| SCHEMBL7873708 | 0.85 | CYP19A1 (0.51) | ALDH1A1KMT2ASMN1; SMN2CYP19A1LMNA | |
| SCHEMBL7879552 | 0.82 | CYP19A1 (0.64) | ALDH1A1KMT2ACYP19A1MEN1POLB | |
| SCHEMBL7876935 | 0.79 | SMN1; SMN2 (0.56) | ALDH1A1KMT2ASMN1; SMN2CYP19A1HTT | |
| SCHEMBL7879544 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL8445910 | 0.77 | CYP19A1 (0.47) | KMT2ASMN1; SMN2CYP19A1MEN1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326500-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | ABBOTT LABORATORIES | 2001-12-04 | — | — | US | disclosed |
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |