Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | QPCT | Q16769 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7873778 | 0.89 | CYP19A1 (0.54) | CYP19A1POLBALDH1A1 | |
| SCHEMBL7873708 | 0.86 | CYP19A1 (0.51) | CYP19A1POLBALDH1A1KMT2A | |
| SCHEMBL7873784 | 0.85 | ALDH1A1 (0.55) | CYP19A1POLBQPCTALDH1A1KMT2A | |
| SCHEMBL7868654 | 0.84 | ALDH1A1 (0.52) | CYP19A1POLBALDH1A1MEN1KMT2A | |
| SCHEMBL7876913 | 0.83 | ALDH1A1 (0.53) | CYP19A1POLBALDH1A1KMT2A | |
| SCHEMBL7879591 | 0.82 | ALDH1A1 (0.52) | CYP19A1POLBALDH1A1MEN1KMT2A | |
| SCHEMBL7876919 | 0.79 | ALDH1A1 (0.46) | POLBALDH1A1MEN1KMT2A | |
| SCHEMBL9268617 | 0.76 | ALDH1A1 (0.42) | CYP19A1POLBALDH1A1MEN1KMT2A | |
| SCHEMBL8445910 | 0.74 | CYP19A1 (0.47) | CYP19A1POLBQPCTMEN1KMT2A | |
| SCHEMBL7877032 | 0.74 | ALDH1A1 (0.60) | POLBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326500-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | ABBOTT LABORATORIES | 2001-12-04 | — | — | US | disclosed |
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |