Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7879578 | 0.99 | SMN1; SMN2 (0.43) | TBXAS1SMN1; SMN2MAPK1HTTALDH1A1 | |
| SCHEMBL7868601 | 0.87 | ALDH1A1 (0.47) | TBXAS1SMN1; SMN2MAPK1HTTALDH1A1 | |
| SCHEMBL7876933 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPK1HTTKMT2AQPCT | |
| SCHEMBL7873915 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPK1HTTALDH1A1KMT2A | |
| SCHEMBL7875258 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPK1HTTKMT2AMEN1 | |
| SCHEMBL7875252 | 0.77 | CYP19A1 (0.48) | SMN1; SMN2MAPK1HTTALDH1A1KMT2A | |
| SCHEMBL7873773 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPK1HTTKMT2AQPCT | |
| SCHEMBL7868564 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1KMT2ACYP19A1MEN1 | |
| SCHEMBL8949449 | 0.76 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1KMT2ACYP19A1QPCT | |
| SCHEMBL7868767 | 0.76 | CYP19A1 (0.47) | TBXAS1KMT2ACYP19A1QPCTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326500-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | ABBOTT LABORATORIES | 2001-12-04 | — | — | US | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |