Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7877064 | 0.98 | KMT2A (0.47) | CYP19A1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL7911697 | 0.78 | ALDH1A1 (0.38) | ALDH1A1LMNAHTTPOLBMAPK1 | |
| SCHEMBL7868601 | 0.78 | ALDH1A1 (0.47) | CYP19A1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL7873787 | 0.77 | TBXAS1 (0.44) | CYP19A1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL8949449 | 0.77 | ALDH1A1 (0.56) | CYP19A1KMT2AALDH1A1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL7879578 | 0.76 | SMN1; SMN2 (0.43) | CYP19A1KMT2AALDH1A1HTTMEN1 | |
| Hydrochloric Acid SCHEMBL8949432 | 0.76 | ALDH1A1 (0.55) | CYP19A1KMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL7879575 | 0.76 | TSHR (0.37) | CYP19A1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL7873708 | 0.75 | CYP19A1 (0.51) | CYP19A1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL7868564 | 0.75 | SMN1; SMN2 (0.58) | CYP19A1KMT2AALDH1A1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326500-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | ABBOTT LABORATORIES | 2001-12-04 | — | — | US | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |