Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1063249 | 0.96 | TSHR (0.49) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL27424756 | 0.93 | TSHR (0.49) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL7803052 | 0.91 | THRB (0.46) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL1066699 | 0.91 | THRB (0.48) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL21066707 | 0.90 | TSHR (0.47) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL21066659 | 0.90 | TSHR (0.47) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL1067387 | 0.87 | THRB (0.47) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL3307221 | 0.86 | HCAR2 (0.40) | TSHRALDH1A1CYP3A4LMNANPC1 | |
| SCHEMBL27323436 | 0.86 | TSHR (0.42) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL7804589 | 0.86 | THRB (0.48) | TSHRHPGDTHRBALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6309708-B1 | ORGANOMETALLIC POLYMERS | DAIKIN INDUSTRIES, LTD. (JP) | 2001-10-30 | — | — | US | disclosed |