SCHEMBL7873997

SCHEMBL7873997

Oc1c(Br)cc(CCc2cc(Br)c(O)c(Br)c2)cc1Br

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.55
TSHR P16473 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
PTPN1 P18031 2/20 0.45
TTR P02766 2/20 0.44
HSD17B10 Q99714 2/20 0.44
MEN1 O00255 1/20 0.44
ALB P02768 1/20 0.44
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
CASP1 P29466 1/20 0.44
RECQL P46063 1/20 0.44
HIF1A Q16665 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2420912 0.89 CYP3A4 (0.50) CYP3A4TSHRTDP1PTPN1TTR
SCHEMBL2925262 0.87 TDP1 (0.48) CYP3A4TSHRTDP1PTPN1TTR
SCHEMBL28345930 0.86 CRHBP (0.54) CYP3A4TSHRTDP1PTPN1MEN1
SCHEMBL542182 0.85 CYP3A4 (0.46) CYP3A4TSHRTDP1PTPN1TTR
SCHEMBL18986915 0.85 CYP3A4 (0.46) CYP3A4TSHRTDP1PTPN1TTR
SCHEMBL11807477 0.85 TDP1 (0.46) CYP3A4TSHRTDP1PTPN1TTR
Bromide SCHEMBL28429836 0.83 TDP1 (0.44) CYP3A4TSHRTDP1PTPN1TTR
SCHEMBL2921636 0.83 TNKS2 (0.48) CYP3A4TSHRTDP1PTPN1TTR
SCHEMBL35308 0.82 PTPN1 (0.61) CYP3A4TSHRTDP1PTPN1TTR
SCHEMBL9145508 0.81 NPC1 (0.55) CYP3A4TSHRTDP1TTRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6168649-B1 THIN DISCRIMINATING LAYER SELECTED FROM THE GROUP CONSISTING OF POLYCARBONATE, POLYESTER, AND POLYESTERCARBONATE. MG GENERON, INC. 2001-01-02 US disclosed
EP-0739879-B1 Halogen-containing cyanate ester, process for producing the same and thermosetting resin composition containing the same SUMITOMO CHEMICAL CO (JP) 1999-12-22 EP disclosed
EP-0739879-A1 Halogen-containing cyanate ester, process for producing the same and thermosetting resin composition containing the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-10-30 EP disclosed
EP-0400948-A2 Heat-resistant, flame-retardant epoxy resin compositions MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-12-05 EP disclosed
US-4150068-A OLIGOMERIC POLYHALOPHOSPHATE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1979-04-17 US disclosed