Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7866860 | 0.99 | ALDH1A1 (0.54) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| Hydrochloric Acid SCHEMBL7869916 | 0.87 | ALDH1A1 (0.59) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| SCHEMBL7870712 | 0.87 | BCAT2 (0.51) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| SCHEMBL7874103 | 0.87 | ALDH1A1 (0.56) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| Hydrochloric Acid SCHEMBL7862117 | 0.86 | ALDH1A1 (0.55) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| Hydrochloric Acid SCHEMBL7870715 | 0.86 | BCAT2 (0.50) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| SCHEMBL7866940 | 0.84 | HTT (0.58) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| SCHEMBL7868753 | 0.84 | ALDH1A1 (0.62) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| Hydrochloric Acid SCHEMBL7868785 | 0.83 | HTT (0.57) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| Hydrochloric Acid SCHEMBL7862082 | 0.83 | ALDH1A1 (0.61) | ALDH1A1KDM4EKMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300368-B1 | FOR THERAPY OF ATRIAL ARRHYTHMIA | MITSUI CHEMICALS, INC. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0968999-A1 | Anilide derivatives and antiarrhythmic agents containing the same | Mitsui Chemicals, Inc. (JP) | 2000-01-05 | — | — | EP | disclosed |