Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 6/20 | 0.47 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7873994 | 0.99 | P2RX3 (0.47) | P2RX3ABL1CNR1CNR2KDM4E | |
| Hydrochloric Acid SCHEMBL7862091 | 0.85 | LMNA (0.40) | P2RX3ABL1CNR1CNR2MAPT | |
| SCHEMBL7869785 | 0.84 | HRH3 (0.49) | MAPTPOLBSIRT2 | |
| Hydrochloric Acid SCHEMBL7866529 | 0.83 | HRH3 (0.48) | MAPTPOLBSIRT2 | |
| Hydrochloric Acid SCHEMBL7868487 | 0.79 | ABL1 (0.40) | P2RX3ABL1MAPT | |
| SCHEMBL7862201 | 0.78 | ACACB (0.47) | MAPTPOLBEPHX2 | |
| Hydrochloric Acid SCHEMBL7869860 | 0.77 | ACACB (0.46) | ABL1MAPTPOLB | |
| SCHEMBL7866950 | 0.75 | LMNA (0.48) | KDM4EMAPTPOLB | |
| Hydrochloric Acid SCHEMBL7874134 | 0.74 | LMNA (0.47) | KDM4EMAPTPOLB | |
| Hydrochloric Acid SCHEMBL7870706 | 0.73 | MCHR1 (0.48) | KDM4EMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300368-B1 | FOR THERAPY OF ATRIAL ARRHYTHMIA | MITSUI CHEMICALS, INC. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0968999-A1 | Anilide derivatives and antiarrhythmic agents containing the same | Mitsui Chemicals, Inc. (JP) | 2000-01-05 | — | — | EP | disclosed |