Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 5/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869231 | 1.00 | F13A1 (0.35) | F13A1ACHEHSP90AA1HSP90AB1PAOX | |
| SCHEMBL5727974 | 0.65 | — | — | |
| SCHEMBL1273822 | 0.60 | CA12 (0.45) | F13A1HSP90AA1HSP90AB1 | |
| SCHEMBL15212634 | 0.60 | GRIN2D (0.42) | F13A1PAOX | |
| SCHEMBL1272863 | 0.60 | CA12 (0.45) | F13A1HSP90AA1HSP90AB1 | |
| SCHEMBL7874399 | 0.60 | HRH1 (0.34) | — | |
| SCHEMBL9489416 | 0.59 | ALDH1A1 (0.67) | F13A1HSP90AA1HSP90AB1 | |
| SCHEMBL20538899 | 0.59 | ALDH1A1 (0.67) | F13A1HSP90AA1HSP90AB1 | |
| SCHEMBL26107919 | 0.59 | ALDH1A1 (0.67) | F13A1HSP90AA1HSP90AB1 | |
| SCHEMBL1274316 | 0.58 | CA12 (0.46) | F13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010041794-A1 | Nucleotide analogs | GILEAD SCIENCES, INC. | 2001-11-15 | — | — | US | claimed |
| EP-0719273-A1 | NUCLEOTIDE ANALOGS | GILEAD SCIENCES, INC. (US) | 1996-07-03 | — | — | EP | claimed |
| WO-1995007920-A1 | NUCLEOTIDE ANALOGS | GILEAD SCIENCES, INC. (US) | 1995-03-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010041794-A1 | Nucleotide analogs | PNP, NUDT1, TYMP | F13A1 2527/4885ACHE 2471/4885HSP90AA1 2153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.