Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2302763 | 0.85 | ALDH1A1 (0.49) | TSHRALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL3236704 | 0.84 | TSHR (0.54) | TSHRALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL28416837 | 0.80 | TSHR (0.50) | TSHRALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL4486338 | 0.77 | TSHR (0.62) | TSHRALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL2933671 | 0.76 | — | — | |
| SCHEMBL4623846 | 0.76 | — | — | |
| SCHEMBL2933673 | 0.76 | — | — | |
| SCHEMBL15245 | 0.76 | — | — | |
| SCHEMBL4895623 | 0.76 | TSHR (0.68) | TSHRALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL86235 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010055461-A1 | METHOD FOR PRODUCING AN OPTICAL WAVEGUIDE | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 2001-12-27 | — | — | US | disclosed |
| EP-0943935-A2 | Optical waveguide and method for production thereof | Nippon Telegraph and Telephone Corporation (JP) | 1999-09-22 | — | — | EP | disclosed |