SCHEMBL2302763

SCHEMBL2302763

FC(F)C(F)COCC1CO1

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.49
TSHR P16473 3/20 0.46
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
TDP1 Q9NUW8 2/20 0.38
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7874503 0.85 TSHR (0.45) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL86235 0.82
SCHEMBL3236704 0.81 TSHR (0.54) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL28416837 0.77 TSHR (0.50) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL23248792 0.77 TSHR (0.54) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL65567 0.77 ALDH1A1 (0.60) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL36444 0.76 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL22592522 0.76 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL17011976 0.76 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL13568053 0.76 TSHR (0.48) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090264572-A1 COATING COMPOSITIONS AND USES THEREOF ETERNAL CHEMICAL CO., LTD. (TW) 2009-10-22 US claimed
CN-103613974-A Coating composition and use thereof ETERNAL CHEMICAL CO LTD 2014-03-05 CN disclosed
US-7989581-B2 Polyether from ring-opening of glycidyl ether with (C2-C5 alkylene oxide) monohydric alcohol DOW CORNING TORAY COMPANY, LTD. (JP) 2011-08-02 US disclosed
US-20100022732-A1 Polyether And Method For Producing The Same DOW CORNING TORAY COMPANY, LTD. (JP) 2010-01-28 US disclosed
CN-101565573-A Coating composition and use thereof ETERNAL CHEMICAL CO LTD (CN) 2009-10-28 CN disclosed
US-20090264572-A1 COATING COMPOSITIONS AND USES THEREOF ETERNAL CHEMICAL CO., LTD. (TW) 2009-10-22 US disclosed
EP-2022808-A1 POLYETHER AND METHOD FOR PRODUCING THE SAME Dow Corning Toray Co., Ltd. (JP) 2009-02-11 EP disclosed