SCHEMBL7874523

SCHEMBL7874523

Cc1ccc(S(=O)(=O)NC(C)C(C)N)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 1/20 0.57
GAA P10253 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
CA2 P00918 7/20 0.56
CA9 Q16790 5/20 0.56
ALDH1A1 P00352 4/20 0.56
CA12 O43570 2/20 0.56
TSHR P16473 1/20 0.56
SLC1A3 P43003 1/20 0.55
SLC1A2 P43004 1/20 0.55
SLC1A1 P43005 1/20 0.55
CA1 P00915 6/20 0.54
CA7 P43166 2/20 0.54
MMP2 P08253 4/20 0.53
CA14 Q9ULX7 1/20 0.53
MMP9 P14780 4/20 0.50
MMP1 P03956 3/20 0.50
MMP13 P45452 3/20 0.50
MMP8 P22894 2/20 0.50
MMP3 P08254 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6435458 0.93 ALDH1A1 (0.55) GBA1GAASMN1; SMN2CA2CA9
SCHEMBL25650178 0.88 GAA (0.65) GBA1GAASMN1; SMN2CA2CA9
SCHEMBL3415855 0.85 GBA1 (0.61) GBA1GAASMN1; SMN2CA2CA9
SCHEMBL10289397 0.85 CA2 (0.62) GBA1GAASMN1; SMN2CA2CA9
SCHEMBL7872813 0.83 SMN1; SMN2 (0.54) GBA1SMN1; SMN2CA2CA9ALDH1A1
SCHEMBL30613610 0.81 MMP2 (0.57) GBA1GAASMN1; SMN2CA2CA9
SCHEMBL6500063 0.80 CA2 (0.62) GBA1GAASMN1; SMN2CA2CA9
SCHEMBL19165633 0.77 GAA (0.52) GBA1GAASMN1; SMN2CA2CA9
SCHEMBL19165392 0.77 GAA (0.52) GBA1GAASMN1; SMN2CA2CA9
SCHEMBL15705231 0.77 SLC1A3 (0.55) GBA1GAASMN1; SMN2CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6323174-B1 PERFUME COMPOSITION AT LEAST COMPRISING 4-METHYL-5-HEXEN-1-AL TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-11-27 US disclosed
US-6239324-B1 REACTING A 1,3-BUTADIENE WITH OLEFIN IN PRESENCE OF HYDROPHILIC SOLVENT AND RUTHENIUM COMPOUND TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-05-29 US disclosed