Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.43 |
| ▸ | CCR9 | P51686 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869468 | 0.90 | EPHX2 (0.44) | EGFRP4HTMEPHX2L3MBTL1 | |
| SCHEMBL7870559 | 0.88 | EGFR (0.41) | EGFRP4HTMEPHX2 | |
| SCHEMBL7874499 | 0.87 | P4HTM (0.58) | EGFRP4HTMHDAC3HDAC4HDAC1 | |
| SCHEMBL8867851 | 0.86 | P4HTM (0.53) | SCN3AEGFRP4HTMCCR9PPARD | |
| SCHEMBL7869455 | 0.85 | P4HTM (0.57) | EGFRP4HTM | |
| SCHEMBL7871651 | 0.85 | BCL2L1 (0.46) | EGFRP4HTMHDAC3HDAC4HDAC1 | |
| SCHEMBL7870344 | 0.84 | EPHX2 (0.43) | EGFRP4HTMEPHX2L3MBTL1 | |
| SCHEMBL7870464 | 0.83 | BCL2L1 (0.45) | MMP2MMP9MMP14L3MBTL1MMP8 | |
| SCHEMBL7871681 | 0.83 | EGFR (0.46) | EGFRP4HTMEPHX2 | |
| SCHEMBL7871631 | 0.83 | P4HTM (0.52) | SCN3AEGFRP4HTMCCR9HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |