Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6429489 | 1.00 | FKBP1A (0.31) | FKBP1ANPSR1 | |
| SCHEMBL2006948 | 0.95 | USP2 (0.31) | — | |
| SCHEMBL7245081 | 0.88 | FFAR3 (0.32) | — | |
| SCHEMBL17157141 | 0.78 | FFAR3 (0.36) | — | |
| SCHEMBL17157143 | 0.78 | FFAR3 (0.36) | — | |
| SCHEMBL2683916 | 0.77 | USP2 (0.39) | — | |
| SCHEMBL611149 | 0.76 | FKBP1A (0.32) | FKBP1A | |
| Hydrochloric Acid SCHEMBL10884122 | 0.76 | USP2 (0.38) | — | |
| SCHEMBL7324549 | 0.75 | FFAR3 (0.33) | — | |
| SCHEMBL12193293 | 0.75 | CNR2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316405-B1 | CYCLOSPORIN A, POLYPEPTIDES, COMPONENT OF AMYLOID PLAQUES FOUND IN NEUROLOGICAL DISORDERS SUCH AS ALZHEIMER'S DISEASE, MULTIPLE SCLEROSIS, AND AMYOTROPHIC LATERAL SCLEROSIS. THE CONJUGATES ARE USEFUL IN THE TREATMENT OF NEUROLOGICAL | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2001-11-13 | — | — | US | disclosed |
| WO-1999010374-A1 | CYCLOSPORIN A CONJUGATES AND USES THEREFOR | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1999-03-04 | — | — | WO | disclosed |