Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.75 |
| ▸ | PARP1 | P09874 | 4/20 | 0.62 |
| ▸ | AR | P10275 | 1/20 | 0.62 |
| ▸ | DAO | P14920 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TYMP | P19971 | 1/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17285573 | 0.86 | ALDH1A1 (1.00) | HPGDALDH1A1CYP2C9PARP1AR | |
| SCHEMBL23885984 | 0.82 | PARP1 (0.54) | HPGDALDH1A1CYP2C9PARP1AR | |
| SCHEMBL30020436 | 0.80 | ALDH1A1 (0.51) | HPGDALDH1A1CYP2C9PARP1AR | |
| SCHEMBL23886051 | 0.80 | ALDH1A1 (0.51) | HPGDALDH1A1CYP2C9PARP1AR | |
| SCHEMBL12474423 | 0.77 | DAO (0.73) | HPGDALDH1A1CYP2C9PARP1AR | |
| SCHEMBL863462 | 0.76 | AR (1.00) | CYP2C9PARP1ARLMNACYP3A4 | |
| SCHEMBL10743236 | 0.75 | PARP1 (0.63) | HPGDALDH1A1CYP2C9PARP1AR | |
| SCHEMBL6240087 | 0.72 | PARP1 (0.50) | HPGDALDH1A1CYP2C9PARP1AR | |
| SCHEMBL20204711 | 0.71 | CAPN1 (0.63) | HPGDALDH1A1CYP2C9PARP1AR | |
| SCHEMBL11816803 | 0.71 | ALDH1A1 (0.53) | HPGDALDH1A1CYP2C9PARP1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303603-B1 | FOR THEARPY OF ANXIETY, DEPRESSION, SCHIZOPHRENIA | PIERRE FABRE MEDICAMENT (FR) | 2001-10-16 | — | — | US | disclosed |