Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.63 |
| ▸ | AR | P10275 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | DAO | P14920 | 2/20 | 0.51 |
| ▸ | TYMP | P19971 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL863462 | 0.77 | AR (1.00) | PARP1ARCYP2C9LMNACYP3A4 | |
| SCHEMBL7874800 | 0.75 | HPGD (0.75) | PARP1ARHPGDALDH1A1CYP2C9 | |
| SCHEMBL4447628 | 0.74 | PARP1 (0.46) | PARP1ARHPGDALDH1A1CYP2C9 | |
| SCHEMBL9465535 | 0.73 | NR1H2 (0.61) | PARP1ARHPGDALDH1A1CYP2C9 | |
| SCHEMBL17285573 | 0.72 | ALDH1A1 (1.00) | PARP1ARHPGDALDH1A1CYP2C9 | |
| SCHEMBL1249701 | 0.72 | PARP1 (0.76) | PARP1 | |
| SCHEMBL29349943 | 0.72 | LMNA (1.00) | PARP1ARALDH1A1CYP2C9LMNA | |
| SCHEMBL25546738 | 0.72 | PARP1 (0.71) | PARP1ARHPGDALDH1A1CYP2C9 | |
| SCHEMBL1789242 | 0.72 | LMNA (1.00) | PARP1ARALDH1A1CYP2C9LMNA | |
| SCHEMBL9652743 | 0.72 | HTR2C (0.46) | PARP1ARLMNADAOCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213071-A1 | Process for the preparation of fibre-reactive azo compounds | CIBA-GEIGY AG (CH) | 1987-03-04 | — | — | EP | disclosed |
| EP-0126025-A1 | Process for dyeing silk or silk-containing fibrous material blends | CIBA-GEIGY AG (CH) | 1984-11-21 | — | — | EP | disclosed |