⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27813016 | 0.82 | — | — | |
| SCHEMBL906813 | 0.81 | — | — | |
| SCHEMBL2344865 | 0.81 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL27756824 | 0.81 | EPHX1 (0.50) | — | |
| SCHEMBL11546997 | 0.79 | — | — | |
| SCHEMBL27906395 | 0.79 | — | — | |
| SCHEMBL3896933 | 0.77 | MMP1 (0.47) | — | |
| SCHEMBL11189746 | 0.77 | METAP2 (0.46) | — | |
| SCHEMBL22751568 | 0.77 | METAP2 (0.46) | — | |
| SCHEMBL22956022 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118207652-A | High-strength antibacterial acrylic fiber and preparation process thereof | 南通金余纺塑有限公司 | 2024-06-18 | — | — | CN | claimed |
| US-6329400-B1 | INHIBITION OR ANTAGONISM OF MATRIX METALLOPROTEASES, AND/OR TUMOR NECROSIS FACTOR-ALPHA; EXTRACELLULAR MATRIX DEGRADATION, INHIBITION OF SHEDDING OF CELL SURFACE PROTEIN ECTODOMAINS AND CD23 PROTEOLYSIS | GLAXO WELLCOME INC. | 2001-12-11 | — | — | US | disclosed |