Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.55 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.48 |
| ▸ | FAP | Q12884 | 1/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7865763 | 0.80 | ACHE (0.52) | CACNA1BMAPTKDM4EALDH1A1GAA | |
| SCHEMBL13826412 | 0.73 | KDM4E (0.52) | MAPTKDM4EALDH1A1GAACASP1 | |
| SCHEMBL30275096 | 0.73 | EIF2AK3 (0.44) | MAPTKDM4EALDH1A1GAACASP1 | |
| SCHEMBL16003084 | 0.73 | KDM4E (0.53) | MAPTKDM4EALDH1A1GAACASP1 | |
| SCHEMBL21809066 | 0.71 | KDM4E (0.46) | MAPTKDM4EALDH1A1GAAHDAC1 | |
| SCHEMBL5264907 | 0.71 | CACNA2D1 (1.00) | CACNA2D1CACNA1BCACNB1CACNA1CCACNA1H | |
| SCHEMBL14487344 | 0.71 | KDM4E (0.57) | MAPTKDM4EALDH1A1GAACASP1 | |
| SCHEMBL7388086 | 0.70 | CACNA2D1 (0.67) | CACNA2D1CACNA1BCACNB1CACNA1CDPP8 | |
| SCHEMBL5446443 | 0.70 | GPX4 (0.76) | CACNA2D1CACNA1BCACNB1CACNA1CALDH1A1 | |
| SCHEMBL6488661 | 0.70 | CACNA2D1 (0.67) | CACNA2D1CACNA1BCACNB1CACNA1CDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H2007-H1 | INSECTICIDES | FMC CORPORATION | 2001-12-04 | — | — | US | disclosed |
| WO-1997026252-A1 | INSECTICIDAL N-HETEROCYCLYLALKYL- OR N-[(POLYCYCLYL)-ALKYL]-N'-SUBSTITUTED PIPERAZINES | FMC CORPORATION (US) | 1997-07-24 | — | — | WO | disclosed |