Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7875169 | 0.80 | CACNA2D1 (0.55) | LMNAMAPTGAAALDH1A1HTT | |
| SCHEMBL28788491 | 0.79 | HTT (0.56) | MAPTGAAHTR7HTR2ADRD2 | |
| SCHEMBL26508424 | 0.78 | HTR2A (0.68) | MAPTGAAHTR7HTR2ADRD2 | |
| SCHEMBL11679502 | 0.77 | HTT (0.54) | MAPTGAAHTR7HTR2ADRD2 | |
| SCHEMBL11734080 | 0.77 | HTR2A (0.45) | MAPTHTR7HTR2ADRD2ALDH1A1 | |
| SCHEMBL11840524 | 0.76 | CYP2D6 (0.51) | MAPTHTR7HTR2AALDH1A1TSHR | |
| SCHEMBL11333760 | 0.75 | DRD2 (0.69) | LMNAMAPTHTR7HTR2ADRD2 | |
| SCHEMBL10670064 | 0.74 | TSHR (0.54) | MAPTGAAHTR7HTR2ADRD2 | |
| SCHEMBL10682684 | 0.73 | SIGMAR1 (0.62) | HTR1ASIGMAR1 | |
| SCHEMBL11335321 | 0.72 | HTR1A (0.68) | LMNAMAPTHTR7HTR2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H2007-H1 | INSECTICIDES | FMC CORPORATION | 2001-12-04 | — | — | US | disclosed |
| WO-1997026252-A1 | INSECTICIDAL N-HETEROCYCLYLALKYL- OR N-[(POLYCYCLYL)-ALKYL]-N'-SUBSTITUTED PIPERAZINES | FMC CORPORATION (US) | 1997-07-24 | — | — | WO | disclosed |