Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.86 |
| ▸ | TK2 | O00142 | 5/20 | 0.50 |
| ▸ | TK1 | P04183 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22992433 | 0.93 | RNASE1 (1.00) | RNASE1TK2TK1POLB | |
| SCHEMBL2056750 | 0.93 | RNASE1 (1.00) | RNASE1TK2TK1POLB | |
| SCHEMBL7875892 | 0.93 | RNASE1 (1.00) | RNASE1TK2TK1POLB | |
| SCHEMBL7875887 | 0.93 | RNASE1 (1.00) | RNASE1TK2TK1POLB | |
| SCHEMBL3279568 | 0.93 | RNASE1 (1.00) | RNASE1TK2TK1POLB | |
| SCHEMBL9326675 | 0.84 | RNASE1 (0.82) | RNASE1TK2TK1 | |
| SCHEMBL21886791 | 0.84 | RNASE1 (0.82) | RNASE1TK2TK1 | |
| SCHEMBL13273339 | 0.84 | RNASE1 (0.82) | RNASE1TK2TK1 | |
| SCHEMBL22992340 | 0.84 | RNASE1 (0.82) | RNASE1TK2TK1 | |
| SCHEMBL30976654 | 0.84 | RNASE1 (0.82) | RNASE1TK2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020816-A1 | DETERMINATION OF PRODRUGS METABOLIZABLE BY THE LIVER AND THERAPEUTIC USE THEREOF | YALE UNIVERSITY (US) | 1992-11-26 | — | — | WO | disclosed |