Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7876164 | 1.00 | UTS2R (0.48) | UTS2RPOLBRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL7876351 | 0.78 | RAB9A (0.41) | RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7876350 | 0.78 | RAB9A (0.41) | RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3679353 | 0.74 | FKBP1A (0.60) | — | |
| SCHEMBL7867139 | 0.74 | ITGB2 (0.41) | ALDH1A1SMN1; SMN2CCR1LMNAMAPT | |
| SCHEMBL7867137 | 0.74 | ITGB2 (0.41) | ALDH1A1SMN1; SMN2CCR1LMNAMAPT | |
| SCHEMBL13513299 | 0.73 | UTS2R (0.46) | UTS2RALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7867514 | 0.73 | L3MBTL1 (0.41) | RAB9AALDH1A1SMN1; SMN2LMNATP53 | |
| SCHEMBL7867513 | 0.73 | L3MBTL1 (0.41) | RAB9AALDH1A1SMN1; SMN2LMNATP53 | |
| SCHEMBL11174926 | 0.72 | TACR1 (0.50) | POLBRAB9AALDH1A1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754176-B1 | NOVEL CARBAMATES AND UREAS AS MODIFIERS OF MULTI-DRUG RESISTANCE | VERTEX PHARMA (US) | 2001-12-05 | — | — | EP | claimed |