Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10615959 | 0.86 | CES2 (0.55) | KMT2AMAPTRAB9ASMN1; SMN2CES2 | |
| SCHEMBL16426509 | 0.85 | RAB9A (0.43) | HIF1ATSHRKMT2AMAPTRAB9A | |
| SCHEMBL14884266 | 0.83 | CES2 (0.44) | KMT2AMAPTRAB9ACES2CES1 | |
| SCHEMBL16582498 | 0.83 | KMT2A (0.54) | KMT2AMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10179765 | 0.83 | KMT2A (0.64) | KMT2AMAPTRAB9ANPC1MEN1 | |
| SCHEMBL16603398 | 0.82 | MAOA (0.49) | KMT2AMAPTRAB9ACES2CES1 | |
| SCHEMBL532894 | 0.81 | NPC1 (0.57) | KMT2AMAPTRAB9ANPC1MEN1 | |
| SCHEMBL533375 | 0.81 | NPC1 (0.57) | KMT2AMAPTRAB9ANPC1MEN1 | |
| SCHEMBL9618044 | 0.80 | PRSS1 (0.55) | KMT2AMAPTSMN1; SMN2CES2CES1 | |
| SCHEMBL12199929 | 0.80 | MAOA (0.50) | KMT2AMAPTRAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174573-B1 | 3,4'-(HALO OR HALOGEN),4-((CYCLO)ALK(OXY)CARBONYLOXY)-DIPHENYLACETYLENE COMPOUNDS WHICH INCREASE THE N-I POINT (NEMATIC ANISOTROPY PHASE TRANSITION TEMPERATURE), AND THE DOUBLE REFRACTIVE INDEX | CITIZEN WATCH CO., LTD. (JP) | 2001-01-16 | — | — | US | disclosed |
| US-5972244-A | INCREASE THE N-I POINT, DECREASE VISCOSITY, AND INCREASE DOUBLE REFRACTIVE INDEX OF A LIQUID CRYSTAL COMPOSITION WITHOUT AFFECTING THRESHOLD VOLTAGE | CITIZEN WATCH CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| US-5656198-A | DISPLAY DEVICE | CITIZEN WATCH CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |