Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 12/20 | 0.43 |
| ▸ | RARB | P10826 | 6/20 | 0.43 |
| ▸ | RARG | P13631 | 6/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 4/20 | 0.39 |
| ▸ | RXRG | P48443 | 4/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878338 | 0.80 | RXRA (0.49) | RXRARARBRARGRARARXRB | |
| SCHEMBL7878388 | 0.80 | RXRA (0.48) | RXRARARBRARGRARARXRB | |
| Hydrochloric Acid SCHEMBL7878396 | 0.79 | RXRA (0.48) | RXRARARBRARGRARARXRB | |
| SCHEMBL6250729 | 0.77 | MAPT (0.51) | MCL1EPHX2 | |
| SCHEMBL6318372 | 0.76 | APP (0.59) | APPEPHX2TRPM5 | |
| SCHEMBL4206077 | 0.74 | SLC6A3 (0.46) | MCL1APPEPHX2 | |
| SCHEMBL225811 | 0.74 | EPHX2 (0.49) | MCL1EPHX2 | |
| SCHEMBL15254635 | 0.74 | EPHX2 (0.52) | MCL1EPHX2 | |
| SCHEMBL2741827 | 0.74 | EPHX2 (0.49) | MCL1EPHX2 | |
| SCHEMBL225810 | 0.74 | EPHX2 (0.49) | MCL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326510-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-12-04 | — | — | US | disclosed |
| EP-0901462-A1 | BI-AROMATIC COMPOUNDS, COMPOSITIONS CONTAINING THEM AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1999-03-17 | — | — | EP | disclosed |
| US-5874658-A | PHASE SEPARATION USING ALKANOLAMINE ADDITIVES TO SEPARATE AND SEQUESTER HYDROGEN FLUORIDE AS COMPLEXES AND LIBERATE THE HYDROFLUOROCARBON IN PRESENCE OF SULFURIC ACID AND ALKALI METAL SULFATE | LAROCHE INDUSTRIES INC. (US) | 1999-02-23 | — | — | US | disclosed |
| WO-1998034909-A1 | BI-AROMATIC COMPOUNDS, COMPOSITIONS CONTAINING THEM AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-08-13 | — | — | WO | disclosed |