Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 6/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | IAPP | P10997 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804653 | 0.88 | HTR1A (0.44) | MPOSLC6A4HTR1ATAAR1TSHR | |
| SCHEMBL505600 | 0.82 | TSHR (0.56) | HTR1ATSHRALDH1A1TDP1HSPA5 | |
| SCHEMBL29372814 | 0.82 | TSHR (0.56) | HTR1ATSHRALDH1A1TDP1HSPA5 | |
| SCHEMBL7809714 | 0.80 | TSHR (0.47) | MPOSLC6A4HTR1ATAAR1TSHR | |
| SCHEMBL4967651 | 0.76 | TAAR1 (0.65) | MPOSLC6A4HTR1ATAAR1TSHR | |
| SCHEMBL7876813 | 0.75 | MPO (0.44) | MPOSLC6A4HTR1ATAAR1TSHR | |
| SCHEMBL6706198 | 0.74 | TSHR (0.58) | MPOSLC6A4HTR1ATAAR1TSHR | |
| SCHEMBL10438887 | 0.74 | TAAR1 (0.62) | MPOSLC6A4HTR1ATAAR1TSHR | |
| Ethyne SCHEMBL4194758 | 0.73 | HTR1A (0.56) | MPOSLC6A4HTR1ATAAR1TSHR | |
| SCHEMBL1839662 | 0.73 | TSHR (0.43) | HTR1ATSHRALDH1A1TDP1IAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316170-B2 | COATING, EXPOSURE, DEVELOPMENT AND HEAT TREATMENT | KABUSHIKI KAISHA TOSHIBA (JP) | 2001-11-13 | — | — | US | disclosed |