SCHEMBL787651

SCHEMBL787651

[LiH].c1ccc([SiH](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
TSHR P16473 6/20 0.35
DAO P14920 1/20 0.35
NAPRT Q6XQN6 1/20 0.35
TDP1 Q9NUW8 5/20 0.33
ALOX12 P18054 3/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
CA12 O43570 1/20 0.33
GLA P06280 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA14 Q9ULX7 1/20 0.33
LMNA P02545 1/20 0.33
ACHE P22303 1/20 0.33
CA7 P43166 1/20 0.33
HSD17B10 Q99714 3/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL8221126 0.96 ALDH1A1 (0.35) ALDH1A1TSHRDAONAPRTTDP1
SCHEMBL38902 0.96 ALDH1A1 (0.40) ALDH1A1TSHRDAONAPRTTDP1
Benzene SCHEMBL27873242 0.96 ALDH1A1 (0.40) ALDH1A1TSHRDAONAPRTTDP1
SCHEMBL703965 0.92 ALDH1A1 (0.38) ALDH1A1TSHRDAONAPRTTDP1
Ammonia Solution, Strong SCHEMBL3895204 0.92 ALDH1A1 (0.38) ALDH1A1TSHRDAONAPRTTDP1
SCHEMBL11588969 0.92 ALDH1A1 (0.38) ALDH1A1TSHRDAONAPRTTDP1
SCHEMBL38651919 0.92 ALDH1A1 (0.38) ALDH1A1TSHRDAONAPRTTDP1
SCHEMBL11256956 0.92 ALDH1A1 (0.38) ALDH1A1TSHRDAONAPRTTDP1
Hydrochloric Acid SCHEMBL1400215 0.92 ALDH1A1 (0.38) ALDH1A1TSHRDAONAPRTTDP1
SCHEMBL11589221 0.92 ALDH1A1 (0.38) ALDH1A1TSHRDAONAPRTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117384219-A Organic electroluminescent material and device 环球展览公司 2024-01-12 CN disclosed
US-8575381-B2 Trihydridosilyl-terminated polysilanes and methods of preparation GELEST TECHNOLOGIES, INC. (US) 2013-11-05 US disclosed
US-20120071678-A1 TRIHYDRIDOSILYL-TERMINATED POLYSILANES AND METHODS OF PREPARATION GELEST TECHNOLOGIES, INC. (US) 2012-03-22 US disclosed
US-7041759-B2 Method for the preparation of well-defined metal acetamidinate-based catalysts on solid supports THE UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2006-05-09 US disclosed
US-20040110632-A1 Method for the preparation of well-defined metal acetamidinate-based catalysts on solid supports THE UNIVERSITY OF MARYLAND, COLLEGE PARK 2004-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071678-A1 TRIHYDRIDOSILYL-TERMINATED POLYSILANES AND METHODS OF PREPARATION SI, STT3A, STT3B ALDH1A1 3027/4885TSHR 3039/4885DAO 2741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.