Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.50 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7873479 | 0.87 | MEN1 (0.59) | ALDH1A1RAB9ANPC1TP53SMN1; SMN2 | |
| SCHEMBL10720509 | 0.79 | L3MBTL1 (0.71) | ALDH1A1L3MBTL1TSHRRAB9AKMT2A | |
| SCHEMBL5115066 | 0.79 | L3MBTL1 (0.72) | ALDH1A1L3MBTL1TSHRRAB9ANPC1 | |
| SCHEMBL27767171 | 0.77 | L3MBTL1 (0.71) | ALDH1A1L3MBTL1TSHRRAB9ANPC1 | |
| SCHEMBL18704491 | 0.77 | L3MBTL1 (0.71) | ALDH1A1L3MBTL1TSHRRAB9ANPC1 | |
| SCHEMBL27682978 | 0.77 | L3MBTL1 (0.71) | ALDH1A1L3MBTL1TSHRRAB9ANPC1 | |
| SCHEMBL28294867 | 0.74 | HPGD (0.71) | ALDH1A1L3MBTL1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL10774877 | 0.74 | NR4A2 (0.61) | RAB9ANPC1KMT2A | |
| SCHEMBL29482202 | 0.74 | L3MBTL1 (0.62) | ALDH1A1L3MBTL1TSHRRAB9ANPC1 | |
| SCHEMBL7416946 | 0.74 | KDM4E (0.63) | ALDH1A1L3MBTL1SMN1; SMN2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329502-B1 | VIRICIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS; TREATMENT OF AIDS (ACQUIRED IMMUNE DEFICIENCY SYNDROME) | JAPAN ENERGY CORPORATION (JP) | 2001-12-11 | — | — | US | disclosed |
| US-6313094-B1 | COMPOSITION FOR INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | JAPAN ENERGY CORPORATION (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-0490667-B1 | HIV protease inhibitors | JAPAN ENERGY CORP (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0490667-A2 | HIV protease inhibitors | JAPAN ENERGY CORPORATION (JP) | 1992-06-17 | — | — | EP | disclosed |