Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18704491 | 0.90 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1TSHRRAB9AKMT2A | |
| SCHEMBL177486 | 0.87 | MEN1 (0.67) | L3MBTL1ALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL10720509 | 0.83 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1TSHRRAB9AKMT2A | |
| SCHEMBL3030400 | 0.83 | HPGD (0.57) | L3MBTL1ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL519242 | 0.82 | PHGDH (0.61) | L3MBTL1ALDH1A1TSHRRAB9AKMT2A | |
| SCHEMBL27682978 | 0.82 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1TSHRRAB9AKMT2A | |
| SCHEMBL27767171 | 0.82 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1TSHRRAB9AKMT2A | |
| SCHEMBL7876574 | 0.79 | ALDH1A1 (0.68) | L3MBTL1ALDH1A1TSHRRAB9AKMT2A | |
| SCHEMBL28294867 | 0.79 | HPGD (0.71) | L3MBTL1ALDH1A1TSHRRAB9AKMT2A | |
| SCHEMBL1199986 | 0.77 | L3MBTL1 (0.64) | L3MBTL1ALDH1A1TSHRRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004263-A1 | Ligands of Follicle Stimulating Hormone Receptor and Methods of Use Thereof | ARENA PHARMACEUTICALS, INC. | 2008-01-03 | — | — | US | disclosed |
| WO-2006048331-A1 | 11β-HSD1 INHIBITORS | EVOTEC AG (DE) | 2006-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004263-A1 | Ligands of Follicle Stimulating Hormone Receptor and Methods of Use Thereof | FSHR, GNRHR, LHCGR | L3MBTL1 4498/4885ALDH1A1 1620/4885TSHR 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.