Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868667 | 0.80 | TRPV1 (0.43) | TBXAS1NAMPTHPGDSMN1; SMN2 | |
| SCHEMBL9021023 | 0.78 | HPGD (0.48) | TBXAS1NAMPTHPGDSMN1; SMN2 | |
| SCHEMBL7877318 | 0.78 | CA9 (0.41) | LMNASMN1; SMN2 | |
| SCHEMBL7875230 | 0.77 | TBXAS1 (0.37) | TBXAS1NAMPTCXCR4TERT | |
| SCHEMBL9368177 | 0.76 | NAMPT (0.43) | TBXAS1NAMPTTERT | |
| SCHEMBL9021230 | 0.76 | CA9 (0.38) | SMN1; SMN2 | |
| SCHEMBL7868671 | 0.75 | TAAR1 (0.43) | TBXAS1NAMPTKDM4ETERTLMNA | |
| SCHEMBL7873787 | 0.75 | TBXAS1 (0.44) | TBXAS1LMNAHTTSMN1; SMN2 | |
| SCHEMBL7879555 | 0.75 | TDP1 (0.47) | TBXAS1LMNAHTTSMN1; SMN2 | |
| SCHEMBL7868545 | 0.75 | TBXAS1 (0.39) | TBXAS1NAMPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326500-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | ABBOTT LABORATORIES | 2001-12-04 | — | — | US | disclosed |
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |