Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5377476 | 0.91 | SKP2 (0.48) | TLR8SKP2HSD17B10KDM4EMEN1 | |
| Biphenyl SCHEMBL27834933 | 0.88 | TLR8 (0.43) | TLR8SKP2HSD17B10KDM4EMEN1 | |
| SCHEMBL8076064 | 0.88 | SKP2 (0.43) | TLR8SKP2HSD17B10KDM4EMEN1 | |
| SCHEMBL10424535 | 0.85 | TLR8 (0.44) | TLR8SKP2HSD17B10KDM4EMEN1 | |
| SCHEMBL360103 | 0.83 | ALDH1A1 (0.40) | TLR8SKP2HSD17B10KDM4EMEN1 | |
| SCHEMBL8369434 | 0.82 | IKBKB (0.50) | HSD17B10KDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL11117161 | 0.81 | MEN1 (0.42) | TLR8SKP2HSD17B10KDM4EMEN1 | |
| SCHEMBL22069113 | 0.81 | HSD11B1 (0.45) | TLR8KDM4EGAAMAPTHPGD | |
| SCHEMBL27730914 | 0.81 | PSMB5 (0.42) | TLR8MEN1LMNAGAAMAPT | |
| SCHEMBL7755566 | 0.80 | HTR2A (0.40) | TLR8HSD11B1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323370-B1 | Catalytic process | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2001-11-27 | — | — | US | disclosed |