Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10424535 | 0.94 | TLR8 (0.44) | SKP2ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL8076064 | 0.93 | SKP2 (0.43) | SKP2ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL7876994 | 0.91 | TLR8 (0.44) | SKP2ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL360103 | 0.87 | ALDH1A1 (0.40) | SKP2ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL5380955 | 0.87 | ALDH1A1 (0.45) | SKP2ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL11117161 | 0.86 | MEN1 (0.42) | SKP2ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL30227228 | 0.83 | SKP2 (0.48) | SKP2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL39005 | 0.83 | SKP2 (0.48) | SKP2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL4455067 | 0.82 | SKP2 (0.52) | SKP2ALDH1A1HSD17B10MAPK1MAPT | |
| SCHEMBL8375841 | 0.82 | SKP2 (0.67) | SKP2ALDH1A1HSD17B10MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202359-B2 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2007-04-10 | — | — | US | disclosed |
| US-20050085634-A1 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2005-04-21 | — | — | US | disclosed |
| US-20040068084-A1 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2004-04-08 | — | — | US | disclosed |
| EP-0823459-B1 | Disazo pigment composition and printing ink | DAINIPPON INK & CHEMICALS (JP) | 2002-04-17 | — | — | EP | disclosed |
| US-5803962-A | Disazo pigment composition and printing ink | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-09-08 | — | — | US | disclosed |
| EP-0823459-A2 | Disazo pigment composition and printing ink | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-02-11 | — | — | EP | disclosed |
| US-5493011-A | PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS | HOECHST AG (DE) | 1996-02-20 | — | — | US | disclosed |
| EP-0518909-B1 | WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE | HOECHST AG (DE) | 1994-05-25 | — | — | EP | disclosed |
| EP-0518909-A1 | WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE. | HOECHST AG (DE) | 1992-12-23 | — | — | EP | disclosed |
| WO-1991013941-A1 | WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068084-A1 | Azaoxa heterocyclic compound and method of preparing the same | AOX1, KDM1A, BMI1 | SKP2 2214/4885ALDH1A1 81/4885MEN1 3378/4885 |
| US-20050085634-A1 | Azaoxa heterocyclic compound and method of preparing the same | AOX1, KDM1A, BMI1 | SKP2 1761/4885ALDH1A1 116/4885MEN1 3668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.