Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7883808 | 0.89 | GPR119 (0.44) | GPR119PRCPGRM5MAPTNPC1 | |
| SCHEMBL7877183 | 0.87 | GPR119 (0.36) | GPR119GRM5MAPTNPC1HPGD | |
| SCHEMBL7881578 | 0.87 | GPR119 (0.36) | GPR119GRM5MAPTNPC1HPGD | |
| SCHEMBL505502 | 0.83 | GRM5 (0.45) | GPR119GRM5MAPTNPC1CYP1A2 | |
| SCHEMBL7877288 | 0.79 | GPR119 (0.36) | GPR119PRCPGRM5 | |
| SCHEMBL7885466 | 0.79 | GRM5 (0.39) | GPR119PRCPGRM5MAPTNPC1 | |
| SCHEMBL505666 | 0.79 | GRM5 (0.56) | GPR119GRM5MAPTNPC1CYP1A2 | |
| SCHEMBL505759 | 0.78 | GPR119 (0.43) | GPR119PRCPGRM5MAPTNPC1 | |
| SCHEMBL505795 | 0.78 | GPR119 (0.41) | GPR119PRCPGRM5MAPTNPC1 | |
| SCHEMBL7879218 | 0.77 | GRM5 (0.38) | GPR119PRCPGRM5MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010114971-A1 | COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF | SEPRACOR INC. (US) | 2010-10-07 | — | — | WO | disclosed |