Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.36 |
| ▸ | GRM5 | P41594 | 5/20 | 0.34 |
| ▸ | PRCP | P42785 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.30 |
| ▸ | RAF1 | P04049 | 2/20 | 0.30 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.30 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7883808 | 0.90 | GPR119 (0.44) | GPR119GRM5PRCP | |
| SCHEMBL7882208 | 0.89 | S1PR1 (0.35) | GPR119PRCPACHEALDH1A1 | |
| SCHEMBL7872792 | 0.89 | S1PR1 (0.35) | GPR119PRCPACHEALDH1A1 | |
| SCHEMBL7879696 | 0.87 | NPC1 (0.35) | GPR119PRCPACHEALDH1A1 | |
| SCHEMBL505982 | 0.82 | GRM5 (0.46) | GPR119GRM5PRCPACHEALDH1A1 | |
| SCHEMBL7872804 | 0.82 | PRCP (0.35) | GPR119GRM5PRCPACHEALDH1A1 | |
| SCHEMBL7880734 | 0.82 | GRM5 (0.36) | GPR119GRM5PRCPACHE | |
| SCHEMBL7880996 | 0.81 | RAB9A (0.43) | GPR119GRM5ALDH1A1 | |
| SCHEMBL505120 | 0.79 | PRCP (0.38) | GPR119GRM5PRCPACHEALDH1A1 | |
| SCHEMBL7877057 | 0.79 | GPR119 (0.43) | GPR119GRM5PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010114971-A1 | COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF | SEPRACOR INC. (US) | 2010-10-07 | — | — | WO | disclosed |