Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.55 |
| ▸ | ATP4A | P20648 | 1/20 | 0.50 |
| ▸ | ATP4B | P51164 | 1/20 | 0.50 |
| ▸ | QPCT | Q16769 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868648 | 0.89 | KMT2A (0.53) | NOS1KMT2AMEN1POLBQPCT | |
| SCHEMBL7868710 | 0.87 | QPCT (0.64) | NOS1KMT2AMEN1POLBQPCT | |
| SCHEMBL7877352 | 0.87 | KMT2A (0.63) | NOS1KMT2AMEN1POLBQPCT | |
| SCHEMBL7873818 | 0.86 | PKM (0.59) | NOS1KMT2AMEN1POLBQPCT | |
| SCHEMBL7873758 | 0.86 | TBXAS1 (0.56) | KMT2AMEN1POLBQPCTGAA | |
| Hydrochloric Acid SCHEMBL7873740 | 0.85 | KMT2A (0.64) | KMT2AMEN1POLBQPCTGAA | |
| Hydrochloric Acid SCHEMBL7903386 | 0.85 | PKM (0.58) | NOS1KMT2AMEN1POLBQPCT | |
| SCHEMBL7868600 | 0.84 | QPCT (0.53) | NOS1KMT2AMEN1POLBQPCT | |
| Hydrochloric Acid SCHEMBL7877310 | 0.83 | QPCT (0.51) | NOS1KMT2AMEN1POLBQPCT | |
| SCHEMBL7877344 | 0.82 | TBXAS1 (0.53) | NOS1KMT2AMEN1POLBQPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326500-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | ABBOTT LABORATORIES | 2001-12-04 | — | — | US | disclosed |
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |