Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NOS1 | P29475 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7877310 | 0.98 | QPCT (0.51) | QPCTKMT2AMEN1POLBLMNA | |
| SCHEMBL7868710 | 0.87 | QPCT (0.64) | QPCTKMT2AMEN1POLBLMNA | |
| SCHEMBL7877352 | 0.87 | KMT2A (0.63) | QPCTKMT2AMEN1POLBLMNA | |
| SCHEMBL7873818 | 0.86 | PKM (0.59) | QPCTKMT2AMEN1POLBLMNA | |
| SCHEMBL7868648 | 0.86 | KMT2A (0.53) | QPCTKMT2AMEN1POLBLMNA | |
| SCHEMBL7873758 | 0.86 | TBXAS1 (0.56) | QPCTKMT2AMEN1POLBLMNA | |
| Hydrochloric Acid SCHEMBL7903386 | 0.85 | PKM (0.58) | QPCTKMT2AMEN1POLBLMNA | |
| Hydrochloric Acid SCHEMBL7873740 | 0.85 | KMT2A (0.64) | QPCTKMT2AMEN1POLBLMNA | |
| SCHEMBL7877092 | 0.84 | NOS1 (0.67) | QPCTKMT2AMEN1POLBLMNA | |
| SCHEMBL7875306 | 0.83 | ADRB1 (0.51) | QPCTKMT2AMEN1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326500-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | ABBOTT LABORATORIES | 2001-12-04 | — | — | US | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| US-5780642-A | NON-STEROIDAL ANTIINFLAMMATORY AGENT WHICH BLOCKS RELEASE OF ARACHIDONIC ACID FROM PHOSPHOLIPIDS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |