Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.46 |
| ▸ | LGMN | Q99538 | 3/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7885079 | 0.75 | CDC25A (0.50) | MAPTNPC1RAB9AGAAMEN1 | |
| SCHEMBL1938064 | 0.74 | SLC16A3 (0.51) | SLC16A3LGMNPIK3CAPIK3CBEP300 | |
| SCHEMBL7877169 | 0.72 | KDM4E (0.58) | MAPTSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL26770701 | 0.71 | PDE2A (0.61) | SLC16A3PIK3CAPIK3CBPIK3CDMAPT | |
| SCHEMBL26767064 | 0.71 | PRKDC (0.59) | SLC16A3PIK3CAPIK3CBPIK3CDMAPT | |
| SCHEMBL29888461 | 0.70 | TSHR (0.56) | SLC16A3LGMNMAPTSMN1; SMN2NPC1 | |
| SCHEMBL2400184 | 0.70 | PRKDC (0.51) | SLC16A3LGMNPIK3CAPIK3CBPIK3CD | |
| SCHEMBL24270394 | 0.69 | KDM4E (0.60) | MAPTSMN1; SMN2TP53GAAPRKDC | |
| SCHEMBL14424597 | 0.68 | SLC16A3 (0.58) | SLC16A3MAPTTBK1SMN1; SMN2NPC1 | |
| SCHEMBL13432103 | 0.68 | SLC16A3 (0.52) | SLC16A3MAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6169087-B1 | Modulators of protein tyrosine phosphatases (PTPases) | NOVO NORDISK A/S (DK) | 2001-01-02 | — | — | US | disclosed |
| EP-1017697-A1 | MODULES OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015529-A1 | MODULES OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 1999-04-01 | — | — | WO | disclosed |