Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 9/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | TPMT | P51580 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7003904 | 0.93 | CA1 (0.43) | CA1CA2CA9APPLTA4H | |
| SCHEMBL8142070 | 0.80 | CA2 (0.32) | CA1CA2CA9 | |
| SCHEMBL1262460 | 0.79 | CA1 (0.47) | CA1CA2CA9 | |
| SCHEMBL7881607 | 0.77 | CYP1A2 (0.42) | CA1CA2CA9LTA4H | |
| SCHEMBL7880580 | 0.77 | BCL2L1 (0.40) | CA2 | |
| SCHEMBL7872966 | 0.77 | MAPK1 (0.42) | CA1CA2CA9LTA4H | |
| SCHEMBL2069523 | 0.71 | METAP2 (0.42) | CA1CA2APPTPMT | |
| SCHEMBL75931 | 0.71 | METAP2 (0.42) | CA1CA2APPTPMT | |
| SCHEMBL66792 | 0.71 | METAP2 (0.42) | CA1CA2APPTPMT | |
| SCHEMBL95869 | 0.69 | SOS1 (0.39) | CA1CA2CA9APPCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6333441-B1 | FORMING MIXTURE COMPRISING FORMIC ACID, TRIETHYLAMINE, TRIBUTYLPHOSPHINE, AND TRIS(DIBENZYLIDENEACETONE) DIPALLADIUM (0)-CHLOROFORM ADDUCT IN SOLVENT, ADDING THERETO ALKYNE UNDER EFFECTIVE REDUCTION CONDITIONS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-25 | — | — | US | disclosed |
| EP-0560532-B1 | Preparation of cis-olefins | NISSAN CHEMICAL IND LTD (JP) | 1999-08-04 | — | — | EP | disclosed |
| EP-0560532-A1 | Preparation of cis-olefins | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1993-09-15 | — | — | EP | disclosed |