SCHEMBL75931

SCHEMBL75931

Ic1ccc(-c2ccc(-c3ccc(I)cc3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.42
HDAC8 Q9BY41 2/20 0.41
TPMT P51580 1/20 0.40
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
CYP3A4 P08684 3/20 0.38
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
IDO1 P14902 2/20 0.36
SLC22A2 O15244 1/20 0.36
SLC22A1 O15245 1/20 0.36
SLC22A3 O75751 1/20 0.36
APP P05067 2/20 0.36
FAAH O00519 1/20 0.35
MGLL Q99685 1/20 0.35
GALR1 P47211 1/20 0.34
GSK3B P49841 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL66792 1.00 METAP2 (0.42) METAP2HDAC8TPMTCA1CA2
SCHEMBL2069523 1.00 METAP2 (0.42) METAP2HDAC8TPMTCA1CA2
Water SCHEMBL9600645 0.96 METAP2 (0.40) METAP2HDAC8TPMTCA1CA2
Water SCHEMBL9600843 0.96 METAP2 (0.40) METAP2HDAC8TPMTCA1CA2
SCHEMBL1989297 0.89 ESR1 (0.47) METAP2HDAC8TPMTCA1CA2
SCHEMBL24029558 0.86 ALDH1A1 (0.60) TPMTCA1CA2CYP3A4ALDH1A1
SCHEMBL45621 0.86 ALDH1A1 (0.60) TPMTCA1CA2CYP3A4ALDH1A1
SCHEMBL5858555 0.86 ALDH1A1 (0.60) TPMTCA1CA2CYP3A4ALDH1A1
SCHEMBL10597056 0.85 HDAC8 (0.50) HDAC8TPMTCA1CA2CYP3A4
SCHEMBL67142 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1995234-B1 p-TERPHENYL COMPOUND MIXTURE AND ELECTROPHOTOGRAPHIC PHOTORECEPTORS MADE BY USING THE SAME HODOGAYA CHEMICAL CO LTD (JP) 2016-01-06 EP claimed
US-8673792-B2 p-Terphenyl compound mixture and electrophotographic photoreceptors made by using the same HODOGAYA CHEMICAL CO., LTD. (JP) 2014-03-18 US claimed
US-20130280652-A1 P-TERPHENYL COMPOUND MIXTURE AND ELECTROPHOTOGRAPHIC PHOTORECEPTORS MADE BY USING THE SAME HODOGAYA CHEMICAL CO LTD (JP) 2013-10-24 US claimed
US-7902402-B2 N,N'-bis(4-diphenylaminobiphenyl-4'-yl)-N,N'-diphenyl-4,4''-diamino-p-terphenyl; EL element comprises an anode, a hole transport layer, a light emitting layer, an electron transport layer and a cathode laminated sequentially on a substrate; displays; provides high luminance at low applied voltage HODOGAYA CHEMICAL CO., LTD. (JP) 2011-03-08 US claimed
US-20100174115-A1 TETRAMINE COMPOUND AND ORGANIC EL DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2010-07-08 US claimed
US-20090053633-A1 P-TERPHENYL COMPOUND MIXTURE AND ELECTROPHOTOGRAPHIC PHOTORECEPTORS MADE BY USING THE SAME HODOGAYA CHEMICAL CO., LTD. (JP) 2009-02-26 US claimed
EP-1995234-A1 p-TERPHENYL COMPOUND MIXTURE AND ELECTROPHOTOGRAPHIC PHOTORECEPTORS MADE BY USING THE SAME Hodogaya Chemical Co., Ltd. (JP) 2008-11-26 EP claimed
EP-4131456-B1 ORGANIC LIGHT-EMITTING DEVICE SFC CO LTD (KR) 2026-02-18 EP disclosed
EP-4567018-A1 METHOD FOR PRODUCING FLUORINATED ORGANIC COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2025-06-11 EP disclosed
US-12281248-B2 Organic light-emitting element using polycyclic aromatic derivative compound SFC CO., LTD. (KR) 2025-04-22 US disclosed
EP-3941159-B1 ORGANIC ELECTROLUMINESCENCE ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2025-04-16 EP disclosed
US-20250109145-A1 ORGANIC ELECTROLUMINESCENT DEVICE, AND COMPOUND FOR THE SAME HODOGAYA CHEMICAL CO., LTD. (JP) 2025-04-03 US disclosed
US-12219872-B2 Organic electroluminescent element HODOGAYA CHEMICAL CO., LTD. (JP) 2025-02-04 US disclosed
US-20020102434-A1 Organic EL device TDK CORPORATION (JP) 2002-08-01 US disclosed
US-6344283-B1 OPTICAL AND ELECTRONIC NON-STRUCTURAL TERT-AMINOPHENYLAMINO-SUBSTITUTED MULTIPHENYLENEDIAMINE MATERIAL PARTICULARLY LESS SUSCEPTIBLE TO PHYSICAL CHANGES, PHOTOCHEMICAL CHANGES AND ELECTROCHEMICAL CHANGES TDK CORPORATION (JP) 2002-02-05 US disclosed
EP-0686879-B1 Charge-transporting polymer and organic electronic device using the same FUJI XEROX CO LTD (JP) 2000-05-24 EP disclosed
EP-0891121-A1 ORGANIC ELECTROLUMINESCENT ELEMENTS TDK Corporation (JP) 1999-01-13 EP disclosed
US-5731118-A Charge transporting random copolyester resin, process for producing the same and organic electronic device using the same FUJI XEROX CO., LTD. (JP) 1998-03-24 US disclosed
US-5604064-A USEFUL IN ELECTROPHOTOGRAPHIC PHOTORECEPTORS FUJI XEROX CO., LTD. (JP) 1997-02-18 US disclosed
EP-0686879-A1 Charge-transporting polymer and organic electronic device using the same FUJI XEROX CO., LTD. (JP) 1995-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250109145-A1 ORGANIC ELECTROLUMINESCENT DEVICE, AND COMPOUND FOR THE SAME TYR, AZI2, AOC1 METAP2 1787/4885HDAC8 2128/4885TPMT 34/4885
US-12281248-B2 Organic light-emitting element using polycyclic aromatic derivative compound TRPA1, TYR, ZKSCAN2 METAP2 1228/4885HDAC8 899/4885TPMT 70/4885
US-20100174115-A1 TETRAMINE COMPOUND AND ORGANIC EL DEVICE TTI1, TERT, RIF1 METAP2 3927/4885HDAC8 2349/4885TPMT 1647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.