Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343011 | 0.86 | MAPT (0.77) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL17703534 | 0.84 | NPSR1 (0.82) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL6203117 | 0.81 | MAPT (0.69) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL28784671 | 0.81 | ALDH1A1 (0.56) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL14662953 | 0.81 | MAPT (0.69) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL7877273 | 0.81 | NPSR1 (0.77) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL13204576 | 0.80 | ALDH1A1 (0.60) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL27972914 | 0.79 | NPSR1 (0.74) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL18209598 | 0.76 | RAB9A (0.69) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL14662793 | 0.76 | MEN1 (0.63) | RAB9AMAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6333414-B1 | BY REACTION OF THIOUREA WITH THE CORRESPONDING DIKETONE ESTER; CARRIED OUT UNDER REACTION CONDITIONS, PARTICULARLY WITH RESPECT TO PH, WHICH ARE INDUSTRIALLY MORE FAVORABLE. | L'ORéAL S.A. (FR) | 2001-12-25 | — | — | US | disclosed |