SCHEMBL787778

SCHEMBL787778

CC1=C(C#N)C(=C(C#N)C#N)OC1(c1ccc(-c2ccccc2)cc1)C(F)(F)F

nearest known ligand 0.86

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 9/20 0.86
MGAT2 Q10469 6/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
PRNP P04156 1/20 0.34
PPARG P37231 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
RCE1 Q9Y256 1/20 0.34
NR2E3 Q9Y5X4 1/20 0.34
NCOR2 Q9Y618 1/20 0.34
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL406234 0.93 GPR35 (1.00) GPR35MGAT2MEN1KMT2APRNP
SCHEMBL25594138 0.93 GPR35 (1.00) GPR35MGAT2MEN1KMT2APRNP
SCHEMBL787779 0.90 GPR35 (0.80) GPR35MGAT2MEN1KMT2APRNP
SCHEMBL16158292 0.88 GPR35 (0.67) GPR35MEN1KMT2APRNPPPARG
SCHEMBL24141613 0.85 GPR35 (0.63) GPR35MGAT2MEN1KMT2APRNP
SCHEMBL12837301 0.81 GPR35 (0.79) GPR35
SCHEMBL13302913 0.81 GPR35 (0.79) GPR35
SCHEMBL22830503 0.81 GPR35 (0.79) GPR35
SCHEMBL13852327 0.81 GPR35 (0.67) GPR35MEN1KMT2APRNPPPARG
SCHEMBL20954432 0.81 GPR35 (0.69) GPR35MGAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119013616-A Nonlinear optical chromophores with short-chain bridging structures, low light loss materials containing them and methods of making them 光波逻辑有限公司 2024-11-22 CN disclosed
EP-4460726-A1 NONLINEAR OPTICAL CHROMOPHORES HAVING SHORT-CHAIN BRIDGE STRUCTURES, LOW OPTICAL LOSS MATERIALS CONTAINING THE SAME, AND METHODS FOR PREPARING THE SAME Lightwave Logic, Inc. (US) 2024-11-13 EP disclosed
WO-2023132934-A1 NONLINEAR OPTICAL CHROMOPHORES HAVING SHORT-CHAIN BRIDGE STRUCTURES, LOW OPTICAL LOSS MATERIALS CONTAINING THE SAME, AND METHODS FOR PREPARING THE SAME LIGHTWAVE LOGIC, INC. (US) 2023-07-13 WO disclosed
WO-2023132934-A1 NONLINEAR OPTICAL CHROMOPHORES HAVING SHORT-CHAIN BRIDGE STRUCTURES, LOW OPTICAL LOSS MATERIALS CONTAINING THE SAME, AND METHODS FOR PREPARING THE SAME LIGHTWAVE LOGIC, INC. (US) 2023-07-13 WO disclosed
US-20230212399-A1 Nonlinear Optical Chromophores Having Short-Chain Bridge Structures, Low Optical Loss Materials Containing the Same, and Methods for Preparing the Same LIGHTWAVE LOGIC, INC. (US) 2023-07-06 US disclosed
US-20230183575-A1 Nonlinear Optical Chromophores Having Tetrahydrocarbazole Donor Groups, Lyotropic Compositions Containing the Same, and Methods of Poling Such Compositions LIGHTWAVE LOGIC, INC. (US) 2023-06-15 US disclosed
WO-2023107680-A1 NONLINEAR OPTICAL CHROMOPHORES HAVING TETRAHYDROCARBAZOLE DONOR GROUPS, LYOTROPIC COMPOSITIONS CONTAINING THE SAME, AND METHODS OF POLING SUCH COMPOSITIONS LIGHTWAVE LOGIC, INC. (US) 2023-06-15 WO disclosed
WO-2023102066-A1 NON-LINEAR OPTICAL MATERIALS CONTAINING HIGH BOILING POINT SOLVENTS, AND METHODS OF EFFICIENTLY POLING THE SAME LIGHTWAVE LOGIC, INC. (US) 2023-06-08 WO disclosed
US-20230174852-A1 Non-Linear Optical Materials Containing High Boiling Point Solvents, and Methods of Efficiently Poling the Same LIGHTWAVE LOGIC, INC. (US) 2023-06-08 US disclosed
EP-4172155-A1 NONLINEAR OPTICAL CHROMOPHORES COMPRISING A DIAMONDOID GROUP Lightwave Logic, Inc. (US) 2023-05-03 EP disclosed
CN-115996920-A Nonlinear optical chromophores comprising adamantyl-like groups 光波逻辑有限公司 2023-04-21 CN disclosed
US-9703128-B2 Method for making an integrated circuit having optical data communication BrPhotonics Produtos Optoeletronicos LTDA (BR) 2017-07-11 US disclosed
US-20160349547-A1 METHOD FOR MAKING AN INTEGRATED CIRCUIT HAVING OPTICAL DATA COMMUNICATION LIGHTWAVE LOGIC, INC. 2016-12-01 US disclosed
US-8934741-B2 Integrated circuit with optical data communication Brphotonics Produtos Optoelectronicos LTDA (BR) 2015-01-13 US disclosed
US-20140302250-A1 ELECTRO-OPTIC POLYMER AND ELECTRO-OPTIC DEVICES MADE THEREFROM GIGOPTIX, INC. (US) 2014-10-09 US disclosed
US-8618241-B2 Stabilized electro-optic materials and electro-optic devices made therefrom GIGOPTIX, INC. (US) 2013-12-31 US disclosed
US-20120163749-A1 INTEGRATED CIRCUIT WITH OPTICAL DATA COMMUNICATION GIGOPTIX, INC. (US) 2012-06-28 US disclosed
US-20120157584-A1 STABILIZED ELECTRO-OPTIC MATERIALS AND ELECTRO-OPTIC DEVICES MADE THEREFROM GIGOPTIX, INC. (US) 2012-06-21 US disclosed
WO-2012037377-A2 INTEGRATED CIRCUIT WITH OPTICAL DATA COMMUNICATION GIGOPTIX, INC. (US) 2012-03-22 WO disclosed
WO-2012037372-A2 STABILIZED ELECTRO-OPTIC MATERIALS AND ELECTRO-OPTIC DEVICES MADE THEREFROM GIGOPTIX, INC. (US) 2012-03-22 WO disclosed