Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10244197 | 0.85 | USP2 (0.44) | ALOX15ALDH1A1USP2GAAPKM | |
| SCHEMBL10244133 | 0.85 | USP2 (0.44) | ALOX15ALDH1A1USP2GAAPKM | |
| SCHEMBL15445117 | 0.85 | USP2 (0.44) | ALOX15ALDH1A1USP2GAAPKM | |
| SCHEMBL69138 | 0.85 | ALOX15 (0.48) | ALOX15ALDH1A1USP2GAAPKM | |
| SCHEMBL6536206 | 0.85 | ALOX15 (0.48) | ALOX15ALDH1A1USP2GAAPKM | |
| SCHEMBL22526148 | 0.79 | ALDH1A1 (0.40) | ALOX15ALDH1A1USP2GAAPKM | |
| SCHEMBL681628 | 0.79 | CA1 (0.55) | CA12CA1CA9ALOX15ALDH1A1 | |
| SCHEMBL22694726 | 0.78 | ALDH1A1 (0.39) | ALOX15ALDH1A1USP2GAAPKM | |
| SCHEMBL11671634 | 0.78 | ALDH1A1 (0.48) | ALOX15ALDH1A1USP2GAAPKM | |
| SCHEMBL19304391 | 0.76 | ALDH1A1 (0.38) | ALOX15ALDH1A1USP2GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118207-A1 | PYRAZOLO [1, 5-A] PYRIMIDINE DERIVATIVES AS MTOR INHIBITORS | SCHERING CORPORATION (US) | 2010-10-14 | — | — | WO | disclosed |