Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22288428 | 0.84 | ELANE (0.41) | KMT2AMEN1ELANETHRBLMNA | |
| SCHEMBL1013508 | 0.83 | LMNA (0.57) | KMT2AMEN1ELANELMNAALDH1A1 | |
| SCHEMBL1394964 | 0.79 | PPARG (0.50) | KMT2AMEN1ELANETHRBLMNA | |
| SCHEMBL1097991 | 0.78 | ELANE (0.59) | ELANETHRBLMNARAB9AHTR2A | |
| SCHEMBL14870980 | 0.78 | ELANE (0.73) | KMT2AMEN1ELANE | |
| SCHEMBL8519147 | 0.78 | RAB9A (0.70) | KMT2AMEN1LMNAALDH1A1RAB9A | |
| SCHEMBL609104 | 0.77 | CA1 (0.48) | KMT2AMEN1ELANETHRBLMNA | |
| SCHEMBL611229 | 0.77 | KMT2A (0.45) | KMT2AMEN1ELANETHRBLMNA | |
| SCHEMBL47952 | 0.77 | RAB9A (0.56) | KMT2AMEN1ELANETHRBLMNA | |
| SCHEMBL21379296 | 0.77 | PARP10 (0.59) | KMT2AMEN1ALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3917907-A1 | MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF | Universitá Degli Studi Di Salerno (IT) | 2021-12-08 | — | — | EP | disclosed |
| WO-2020157126-A1 | MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF | Università degli Studi di Salerno (IT) | 2020-08-06 | — | — | WO | disclosed |
| WO-2001056358-A2 | ENHANCED PROPERTIED PESTICIDES | ROHM AND HAAS COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |