Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 17/20 | 0.45 |
| ▸ | PPARA | Q07869 | 15/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879105 | 0.87 | PPARG (0.46) | KDM4EPPARGPPARAHRH3PPARD | |
| SCHEMBL7879102 | 0.87 | PPARG (0.46) | KDM4EPPARGPPARAHRH3PPARD | |
| SCHEMBL7879353 | 0.83 | PIM1 (0.42) | PPARGPPARAHRH3RAB9A | |
| SCHEMBL7879358 | 0.83 | PIM1 (0.42) | PPARGPPARAHRH3RAB9A | |
| SCHEMBL7879355 | 0.83 | PIM1 (0.42) | PPARGPPARAHRH3RAB9A | |
| SCHEMBL4746469 | 0.77 | PPARG (0.73) | PPARGPPARAPPARD | |
| SCHEMBL5795341 | 0.76 | KDM4E (0.54) | KDM4EPPARGPPARAHRH3PPARD | |
| SCHEMBL6970285 | 0.76 | PPARG (0.65) | PPARGPPARAPPARD | |
| SCHEMBL10480772 | 0.76 | KDM4E (0.53) | KDM4EPPARGPPARAHRH3PPARD | |
| SCHEMBL7871522 | 0.76 | PPARG (0.46) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329408-B1 | HYPOCHOLESTEROLEMIC AGENTS; OPTICALLY PURE | PFIZER INC. | 2001-12-11 | — | — | US | disclosed |