Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890428 | 0.90 | FDPS (0.53) | FDPSGPR84FFAR1MAPTBLM | |
| SCHEMBL4448018 | 0.90 | FDPS (0.53) | FDPSGPR84FFAR1MAPTBLM | |
| SCHEMBL10456042 | 0.90 | FDPS (0.53) | FDPSGPR84FFAR1MAPTBLM | |
| SCHEMBL4585287 | 0.90 | FDPS (0.53) | FDPSGPR84FFAR1MAPTBLM | |
| Hydrochloric Acid SCHEMBL5183102 | 0.88 | FDPS (0.52) | FDPSGPR84FFAR1MAPTBLM | |
| Hydrochloric Acid SCHEMBL115347 | 0.88 | FDPS (0.52) | FDPSGPR84FFAR1MAPTBLM | |
| Acetic Acid SCHEMBL28656012 | 0.87 | FDPS (0.49) | FDPSGPR84FFAR1MAPTLCK | |
| Acetic Acid SCHEMBL28670248 | 0.87 | FDPS (0.49) | FDPSGPR84FFAR1MAPTLCK | |
| Acetic Acid SCHEMBL15796437 | 0.83 | GPR84 (0.46) | FDPSGPR84FFAR1MAPTLCK | |
| Acetic Acid SCHEMBL15795421 | 0.83 | GPR84 (0.46) | FDPSGPR84FFAR1MAPTLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144177-A | ANIONIC SURFACTANT, QUATERNARY AMMONIUM SALT | KAO SOAP CO., LTD. (JP) | 1979-03-13 | — | — | US | claimed |
| WO-2001053598-A1 | DRY CLEANING SOLVENT COMPOSITION FOR FABRICS | ALBEMARLE CORPORATION (US) | 2001-07-26 | — | — | WO | disclosed |
| US-4144177-A | ANIONIC SURFACTANT, QUATERNARY AMMONIUM SALT | KAO SOAP CO., LTD. (JP) | 1979-03-13 | — | — | US | disclosed |