Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 4/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5183102 | 1.00 | FDPS (0.52) | FDPSSPHK1LMNAOPRM1CYP2D6 | |
| SCHEMBL8890428 | 0.98 | FDPS (0.53) | FDPSSPHK1LMNAOPRM1CYP2D6 | |
| SCHEMBL10456042 | 0.98 | FDPS (0.53) | FDPSSPHK1LMNAOPRM1CYP2D6 | |
| SCHEMBL4585287 | 0.98 | FDPS (0.53) | FDPSSPHK1LMNAOPRM1CYP2D6 | |
| SCHEMBL4448018 | 0.98 | FDPS (0.53) | FDPSSPHK1LMNAOPRM1CYP2D6 | |
| Acetic Acid SCHEMBL7879478 | 0.88 | FDPS (0.50) | FDPSBLMMAPTLAP3GPR84 | |
| Hydrochloric Acid SCHEMBL8098895 | 0.84 | FDPS (0.50) | FDPSSPHK1LMNAOPRM1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7879375 | 0.84 | FDPS (0.50) | FDPSSPHK1LMNAOPRM1CYP2D6 | |
| Hydrochloric Acid SCHEMBL28525297 | 0.84 | FDPS (0.50) | FDPSSPHK1LMNAOPRM1CYP2D6 | |
| Hydrochloric Acid SCHEMBL5050291 | 0.84 | FDPS (0.50) | FDPSSPHK1LMNAOPRM1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12605325-B2 | Hair styling compositions for improving the elongation of hair curls | L'OREAL (FR) | 2026-04-21 | — | — | US | disclosed |
| US-12599546-B2 | Hair treatment compositions, kits thereof, and methods thereof | L'OREAL (FR) | 2026-04-14 | — | — | US | disclosed |
| US-12589065-B2 | Hair care system, hair care method and use of a hair care system | L'OREAL (FR) | 2026-03-31 | — | — | US | disclosed |
| US-12551422-B2 | Compositions and methods for styling the hair | L'ORÉAL (FR) | 2026-02-17 | — | — | US | disclosed |
| EP-4633589-A1 | HAIR TREATMENT COMPOSITIONS THAT IMPART SHINE AND LUSTER | L'OREAL (FR) | 2025-10-22 | — | — | EP | disclosed |
| US-12383483-B2 | Compositions and methods for styling the hair | L'OREAL (FR) | 2025-08-12 | — | — | US | disclosed |
| US-12290589-B2 | Cosmetic and personal care compositions containing cationic surfactants and anionic compounds | L'OREAL (FR) | 2025-05-06 | — | — | US | disclosed |
| WO-2025085270-A1 | HAIR TREATMENT COMPOSITION WITH CATIONIC SURFACTANT, FATTY ALCOHOLS, AND LOW POLAR OIL | L'OREAL (FR) | 2025-04-24 | — | — | WO | disclosed |
| US-20250127697-A1 | HAIR TREATMENT COMPOSITION WITH CATIONIC SURFACTANT, FATTY ALCOHOLS, AND LOW POLAR OIL | L'OREAL (FR) | 2025-04-24 | — | — | US | disclosed |
| US-12268767-B2 | Compositions and methods for treating hair | L'OREAL (FR) | 2025-04-08 | — | — | US | disclosed |
| WO-2010060601-A1 | BLEACHING/HIGHLIGHTING COMPOSITION | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-06-03 | — | — | WO | disclosed |
| WO-2010060602-A1 | PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-06-03 | — | — | WO | disclosed |
| EP-2191812-A1 | Bleaching/Highlighting composition | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-06-02 | — | — | EP | disclosed |
| EP-2191863-A1 | Composition for the permanent shaping of human hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-06-02 | — | — | EP | disclosed |
| WO-2010046080-A2 | COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046077-A2 | COLOURING COMPOSITION | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-04-29 | — | — | WO | disclosed |
| EP-2177204-A1 | Colouring composition | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-04-21 | — | — | EP | disclosed |
| EP-2177205-A1 | Composition for the permanent shaping of human hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-04-21 | — | — | EP | disclosed |
| WO-2010025894-A2 | CONDITIONING COMPOSITION FOR HAIR | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-03-11 | — | — | WO | disclosed |
| EP-2161016-A1 | Conditioning composition for hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-03-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12605325-B2 | Hair styling compositions for improving the elongation of hair curls | SGMS1, SGMS2, SGPL1 | OPRM1 4634/4885FDPS 4512/4885SPHK1 33/4885 |
| US-12551422-B2 | Compositions and methods for styling the hair | DPM1, PIK3C3, SMURF1 | OPRM1 4519/4885FDPS 3444/4885SPHK1 80/4885 |
| US-12589065-B2 | Hair care system, hair care method and use of a hair care system | ASH2L, ALG3, PLOD3 | OPRM1 3141/4885FDPS 4543/4885SPHK1 1052/4885 |
| US-12599546-B2 | Hair treatment compositions, kits thereof, and methods thereof | EBP, FHIT, BRDT | OPRM1 4244/4885FDPS 3991/4885SPHK1 744/4885 |
| US-20250127697-A1 | HAIR TREATMENT COMPOSITION WITH CATIONIC SURFACTANT, FATTY ALCOHOLS, AND LOW POLAR OIL | SGMS1, SGMS2, POLR1C | OPRM1 1065/4885FDPS 4683/4885SPHK1 56/4885 |
| US-12290589-B2 | Cosmetic and personal care compositions containing cationic surfactants and anionic compounds | CUTA, SGMS1, PHOSPHO1 | OPRM1 4139/4885FDPS 4391/4885SPHK1 180/4885 |
| US-12383483-B2 | Compositions and methods for styling the hair | SGMS1, SGMS2, DPM1 | OPRM1 4716/4885FDPS 3142/4885SPHK1 59/4885 |
| US-12268767-B2 | Compositions and methods for treating hair | UNG, OAT, OTC | OPRM1 4576/4885FDPS 1734/4885SPHK1 3287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.