Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 8/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2006887 | 1.00 | AKR1C3 (0.57) | AKR1C3APEX1RXRARXRBNR4A2 | |
| SCHEMBL31666241 | 0.86 | AKR1C3 (0.68) | AKR1C3APEX1RXRARXRBNR4A2 | |
| SCHEMBL8746671 | 0.86 | AKR1C3 (0.68) | AKR1C3APEX1RXRARXRBNR4A2 | |
| SCHEMBL3893886 | 0.86 | AKR1C3 (0.68) | AKR1C3APEX1RXRARXRBNR4A2 | |
| SCHEMBL8001495 | 0.85 | AKR1C3 (0.38) | AKR1C3KDM4EHTTCYP2C9GAA | |
| SCHEMBL17846896 | 0.84 | AKR1C3 (0.47) | AKR1C3APEX1RXRARXRBNR4A2 | |
| SCHEMBL17846894 | 0.84 | AKR1C3 (0.47) | AKR1C3APEX1RXRARXRBNR4A2 | |
| SCHEMBL28192388 | 0.80 | ALDH1A1 (0.44) | AKR1C3KDM4EMAPT | |
| SCHEMBL433478 | 0.80 | TP53 (0.47) | AKR1C3KDM4EHTTCYP2C9GAA | |
| SCHEMBL7764991 | 0.80 | AKR1C3 (0.61) | AKR1C3APEX1RXRARXRBNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014041362-A1 | UV RADIATION CLEAVABLE COMPOUNDS | UNIVERSITY OF BATH (GB) | 2014-03-20 | — | — | WO | disclosed |
| US-6329546-B1 | FOR INVESTIGATING THE MECHANISM OF ACTION OF A PHYSIOLOGICALLY ACTIVE AMINO ACID COMPOUND SUCH AS GLUTAMIC ACID IN AN ORGANISM | LABORATORY OF MOLECULAR BIOPHOTONICS (JP) | 2001-12-11 | — | — | US | disclosed |
| US-6229020-B1 | REACTING N-SUCCINIMIDYL AND P-NITROPHENYL CINNAMATE DERIVATIVES WITH PHYSIOLOGICALLY ACTIVE SUBSTANCE SUCH AS AN AMINO ACID; PROTECTING AMINO OR HYDROXY GROUPS FOR ANALYSIS OF BIOLOGICAL REACTIONS BY IRRADIATION WITH LIGHT | LABORATORY OF MOLECULAR BIOPHOTONICS (JP) | 2001-05-08 | — | — | US | disclosed |