SCHEMBL433478

SCHEMBL433478

Nc1ccccc1C=C(C(=O)O)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.47
KDM4E B2RXH2 1/20 0.41
MAPT P10636 2/20 0.39
GAA P10253 1/20 0.39
HTT P42858 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
HIF1A Q16665 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
AKR1C3 P42330 1/20 0.36
HDAC3 O15379 1/20 0.36
MAPK1 P28482 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16796026 0.91 TP53 (0.41) TP53KDM4EMAPTGAAHTT
SCHEMBL16287426 0.84 TP53 (0.56) TP53KDM4EHTTCYP1A2CYP3A4
SCHEMBL6552201 0.84 TP53 (0.40) TP53KDM4EMAPTGAAHTT
SCHEMBL7879488 0.80 AKR1C3 (0.57) KDM4EMAPTGAAHTTCYP2C9
SCHEMBL18046463 0.80 MAPT (0.37) MAPTGAACYP1A2CYP3A4CYP2C9
SCHEMBL2006887 0.80 AKR1C3 (0.57) KDM4EMAPTGAAHTTCYP2C9
SCHEMBL18046465 0.80 MAPT (0.37) MAPTGAACYP1A2CYP3A4CYP2C9
SCHEMBL7607193 0.77 NFKB1 (0.53) TP53KDM4EMAPT
SCHEMBL7446722 0.75 ALDH1A1 (0.50) TP53KDM4EMAPTHTTCYP1A2
SCHEMBL11565347 0.75 TP53 (0.47) TP53KDM4EMAPTHTTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1484051-B1 Use of at least one blue-light screening agent to preserve the amount of endogenous carotenoids in the skin, new blue- light screening agents, cosmetic compositions. OREAL (FR) 2013-08-21 EP claimed
WO-2012010554-A1 USE OF COMPOUNDS RESULTING FROM A SUGAR POLYOL OR FROM A DEHYDROGENATED SUGAR POLYOL DERIVATIVE AS A UV-SCREENING AGENT; ANTISUN COMPOSITIONS CONTAINING SAME; AND NOVEL COMPOUNDS L'OREAL (FR) 2012-01-26 WO claimed
US-7534421-B2 s-Triazine compounds bearing at least one para-aminobenzalmalonic salt substituent and photoprotective cosmetic compositions comprised thereof L'OREAL (FR) 2009-05-19 US claimed
US-20090074820-A1 AMINOARYLVINYL-S-TRIAZINE COMPOUNDS AND USES THEREOF L'OREAL (FR) 2009-03-19 US claimed
US-20050008588-A1 Aminoarylvinyl-s-triazine compounds and uses thereof L'OREAL (FR) 2005-01-13 US claimed
US-20040258636-A1 Novel s-triazine compounds bearing at least one para-aminobenzalmalonic salt substituent and photoprotective cosmetic compositions comprised thereof SOCIETE L'OREAL S.A. (FR) 2004-12-23 US claimed
EP-1466908-A1 S-tiazin-derivatives having at least one grafted para-aminobenzalmalonic acid salt and sun screening preparations comprising those derivatives L'OREAL (FR) 2004-10-13 EP claimed
CN-114760982-B Composition comprising a cationic polysaccharide and an anionic antioxidant 莱雅公司 2024-05-31 CN disclosed
WO-2024110352-A1 HYDRATING COMPLEX AND USE IN MOISTURISING COMPOSITIONS LABORATOIRES DE BIOLOGIE VEGETALE YVES ROCHER (FR) 2024-05-30 WO disclosed
WO-2023277194-A1 SUNSCREEN W/O EMULSION L'OREAL (FR) 2023-01-05 WO disclosed
WO-2022234092-A1 Oil-in-water emulsion comprising a particular mixture of surfactants and the combination of at least one starch grafted with an acrylic polymer and of at least one starch not grafted with an acrylic polymer L'OREAL (FR) 2022-11-10 WO disclosed
EP-4076340-A1 SUN CARE COMPOSITION L'OREAL (FR) 2022-10-26 EP disclosed
WO-2012010554-A1 USE OF COMPOUNDS RESULTING FROM A SUGAR POLYOL OR FROM A DEHYDROGENATED SUGAR POLYOL DERIVATIVE AS A UV-SCREENING AGENT; ANTISUN COMPOSITIONS CONTAINING SAME; AND NOVEL COMPOUNDS L'OREAL (FR) 2012-01-26 WO disclosed
US-20040258636-A1 Novel s-triazine compounds bearing at least one para-aminobenzalmalonic salt substituent and photoprotective cosmetic compositions comprised thereof SOCIETE L'OREAL S.A. (FR) 2004-12-23 US disclosed
EP-1484051-A2 Use of at least one blue-light screening agent to preserve the amount of endogenous carotenoids in the skin, new blue- light screening agents, cosmetic compositions. L'OREAL (FR) 2004-12-08 EP disclosed
EP-1466908-A1 S-tiazin-derivatives having at least one grafted para-aminobenzalmalonic acid salt and sun screening preparations comprising those derivatives L'OREAL (FR) 2004-10-13 EP disclosed
US-6517742-B1 2-(butyl 4'-ylaminobenzoate)-4,6-bis((1,3,3,3-tetramethyl-1 -((trimethylsilyl)oxy)disiloxanyl)propyl-3-ylamino)-s-triazine; s-triazine derivatives substituted by at least one silicone group; from cyanuric chloride L'OREAL (FR) 2003-02-11 US disclosed
EP-0841341-B1 Sunscreen agents, and cosmetic compositions containing them OREAL (FR) 1999-04-07 EP disclosed
EP-0841341-A1 Sunscreen agents, and cosmetic compositions containing them L'OREAL (FR) 1998-05-13 EP disclosed
EP-0841341-A1 Sunscreen agents, and cosmetic compositions containing them L'OREAL (FR) 1998-05-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050008588-A1 Aminoarylvinyl-s-triazine compounds and uses thereof TYR, AAAS, ALAD TP53 1686/4885KDM4E 1977/4885MAPT 910/4885
US-20040258636-A1 Novel s-triazine compounds bearing at least one para-aminobenzalmalonic salt substituent and photoprotective cosmetic compositions comprised thereof TYR, KRT18, TST TP53 143/4885KDM4E 497/4885MAPT 1270/4885
US-20090074820-A1 AMINOARYLVINYL-S-TRIAZINE COMPOUNDS AND USES THEREOF TYR, AAAS, ALAD TP53 1661/4885KDM4E 1697/4885MAPT 874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.